Non-injection and injection drug use and STI/HIV risk in the United States: the degree to which sexual risk behaviors versus sex with an STI-infected partner account for infection transmission among drug users.
Non-injection and injection drug use and STI/HIV risk in the United States: the degree to which sexual risk behaviors versus sex with an STI-infected partner account for infection transmission among drug users.
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DOI：
10.1007/s10461-012-0276-0
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发表时间：
2013-03
影响因子：
4.4
通讯作者：
Smyrk, Kristina
中科院分区：
文献类型：
--
作者：
Khan, Maria R.;Berger, Amanda;Hemberg, Jordana;O'Neill, Allison;Dyer, Typhanye Penniman;Smyrk, Kristina
我们使用国家青少年健康纵向研究（N=14,322）来测量非注射可卡因和注射毒品使用与性传播感染（包括HIV / STI）风险在美国年轻人中的关联，并确定介导毒品使用和感染之间关系的因素。答复者被分类为注射毒品使用者、非注射快克可卡因使用者或非快克可卡因使用者或注射毒品使用者。非注射型快克可卡因使用仍然与性传播感染（调整患病率比（APR）： 1.63, 95%置信区间（CI）： 1.10-2.42）和性危险行为（包括多重伴侣关系和不一致使用安全套）独立相关。注射用药与性传播感染密切相关（APR: 2.66, 95% CI: 1.18-5.99）；这种关联似乎是由与感染了性传播感染的伴侣发生性行为介导的，而不是由性危险行为介导的。研究结果强调了在包括注射吸毒者在内的所有吸毒者中降低性风险的重要性，因为他们面临着较高的性传播和肠外传播风险。
We used the National Longitudinal Study of Adolescent Health (N=14,322) to measure associations between non-injection crack-cocaine and injection drug use and sexually transmitted infection including HIV (STI/HIV) risk among young adults in the United States and to identify factors that mediate the relationship between drug use and infection. Respondents were categorized as injection drug users, non-injection crack-cocaine users, or non-users of crack-cocaine or injection drugs. Non-injection crack-cocaine use remained an independent correlate of STI (adjusted prevalence ratio (APR): 1.63, 95% confidence interval (CI): 1.10–2.42) and sexual risk behaviors including multiple partnerships and inconsistent condom use. Injection drug use was strongly associated with STI (APR: 2.66, 95% CI: 1.18–5.99); this association appeared to be mediated by sex with STI-infected partners rather than by sexual risk behaviors. The results underscore the importance of sexual risk reduction among all drug users including IDUs, who face high sexual as well as parenteral transmission risk.
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影响因子：
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