Cardiac Aging: From Basic Research to Therapeutics.
Cardiac Aging: From Basic Research to Therapeutics.
复制标题
心脏衰老:从基础研究到治疗
DOI:
10.1155/2021/9570325
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发表时间:
2021
影响因子:
--
通讯作者:
Li J
中科院分区:
文献类型:
--
作者:
Yan M;Sun S;Xu K;Huang X;Dou L;Pang J;Tang W;Shen T;Li J
With research progress on longevity, we have gradually recognized that cardiac aging causes changes in heart structure and function, including progressive myocardial remodeling, left ventricular hypertrophy, and decreases in systolic and diastolic function. Elucidating the regulatory mechanisms of cardiac aging is a great challenge for biologists and physicians worldwide. In this review, we discuss several key molecular mechanisms of cardiac aging and possible prevention and treatment methods developed in recent years. Insights into the process and mechanism of cardiac aging are necessary to protect against age-related diseases, extend lifespan, and reduce the increasing burden of cardiovascular disease in elderly individuals. We believe that research on cardiac aging is entering a new era of unique significance for the progress of clinical medicine and social welfare.
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影响因子:
13.3
作者:
Chang K;Kang P;Liu Y;Huang K;Miao T;Sagona AP;Nezis IP;Bodmer R;Ocorr K;Bai H
通讯作者:
Bai H
影响因子:
7.8
作者:
ASHFORD, T P;PORTER, K R
通讯作者:
PORTER, K R
影响因子:
7.8
作者:
Dai DF;Karunadharma PP;Chiao YA;Basisty N;Crispin D;Hsieh EJ;Chen T;Gu H;Djukovic D;Raftery D;Beyer RP;MacCoss MJ;Rabinovitch PS
通讯作者:
Rabinovitch PS
DOI:
10.18632/aging.100881
发表时间:
2016-02
期刊:
Aging
影响因子:
--
作者:
Chiao YA;Kolwicz SC;Basisty N;Gagnidze A;Zhang J;Gu H;Djukovic D;Beyer RP;Raftery D;MacCoss M;Tian R;Rabinovitch PS
通讯作者:
Rabinovitch PS
DOI:
10.15252/embj.201592862
发表时间:
2016-04-01
期刊:
The EMBO journal
影响因子:
--
作者:
Correia-Melo C;Marques FD;Anderson R;Hewitt G;Hewitt R;Cole J;Carroll BM;Miwa S;Birch J;Merz A;Rushton MD;Charles M;Jurk D;Tait SW;Czapiewski R;Greaves L;Nelson G;Bohlooly-Y M;Rodriguez-Cuenca S;Vidal-Puig A;Mann D;Saretzki G;Quarato G;Green DR;Adams PD;von Zglinicki T;Korolchuk VI;Passos JF
通讯作者:
Passos JF