Knockdown of DEPTOR inhibits cell proliferation and increases chemosensitivity to melphalan in human multiple myeloma RPMI-8226 cells via inhibiting PI3K/AKT activity

Knockdown of DEPTOR inhibits cell proliferation and increases chemosensitivity to melphalan in human multiple myeloma RPMI-8226 cells via inhibiting PI3K/AKT activity
复制标题

敲低 DEPTOR 通过抑制 PI3K/AKT 活性抑制细胞增殖并增加人多发性骨髓瘤 RPMI-8226 细胞对美法仑的化疗敏感性

DOI:
10.1177/0300060513480920
复制
发表时间:
2013-04
影响因子:
1.6
通讯作者:
Wenzhong Que
Wenzhong Que
中科院分区:
医学4区
文献类型:
--
作者:
Haoran Zhang;Junmin Chen;Zhiyong Zeng;Wenzhong Que

文献摘要

参考文献

相似文献

目的利用短发夹状RNA(ShRNA)敲除DEPTOR基因,探讨DEPTOR基因在多发性骨髓瘤RPMI-8226细胞增殖、凋亡和化疗敏感性中的作用。
Objective The present study determined the role of DEP domain containing mTOR-interacting protein (DEPTOR) in the proliferation, apoptosis and chemosensitivity of RPMI-8226 multiple myeloma cells, using small hairpin RNA (shRNA) to knock down DEPTOR gene
DOI: 10.1182/asheducation-2004.1.237
发表时间: 1997
期刊: The New England journal of medicine
影响因子: --
作者:
J. Harousseau;J. Shaughnessy;P. Richardson
通讯作者: J. Harousseau;J. Shaughnessy;P. Richardson
DOI: 10.1128/mcb.00553-07
发表时间: 2007-11
影响因子: 5.3
作者:
J. Knobloch;I. Schmitz;Katrin Götz;K. Schulze-Osthoff;U. Rüther
通讯作者: J. Knobloch;I. Schmitz;Katrin Götz;K. Schulze-Osthoff;U. Rüther
DOI: 10.1158/1078-0432.ccr-11-0294
发表时间: 2011-03
影响因子: 11.5
作者:
S. Bates
通讯作者: S. Bates
DOI: 10.1016/s0140-6736(14)60493-1
发表时间: 2015-05-30
期刊: LANCET
影响因子: 168.9
作者:
Roellig, Christoph;Knop, Stefan;Bornhaeuser, Martin
通讯作者: Bornhaeuser, Martin
DOI: 10.1102/1470-7330.2004.0010
发表时间: 2004-01-14
期刊: Cancer imaging : the official publication of the International Cancer Imaging Society
影响因子: --
作者:
Collins, Conor D
通讯作者: Collins, Conor D