Identification of a dietary pattern prospectively associated with bone mass in Australian young adults.
Identification of a dietary pattern prospectively associated with bone mass in Australian young adults.
复制标题
确定与澳大利亚年轻人骨量前瞻性相关的饮食模式。
DOI：
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复制
发表时间：
2015
影响因子：
7.1
通讯作者：
W. Oddy
中科院分区：
文献类型：
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作者：
E. H. van den Hooven;G. Ambrosini;Rae;Jenny A. Mountain;L. Straker;J. Walsh;K. Zhu;W. Oddy
背景
相对较少的是知道青春期，这是一个时期的大量骨量增长的饮食模式和骨骼健康之间的关系。
目标
我们根据蛋白质、钙和钾的含量推导出了与骨骼健康相关的膳食模式，并在一组年轻人中研究了其与骨矿物质密度（BMD）、骨面积和骨矿物质含量（BMC）的前瞻性相关性。
设计
这项研究包括1024名年轻的成年人，他们的母亲参加了西澳大利亚州妊娠队列（Raine）研究。饮食信息是从14岁和17岁的食物频率问卷中获得的。膳食模式的特点是根据蛋白质，钙，钾的摄入量与使用降秩回归。BMD、骨面积和BMC在20岁时使用全身双能X线骨密度仪扫描进行估计。
结果
我们确定了两种主要的饮食模式。第一种模式与蛋白质、钙和钾的摄入量呈正相关，并且对低脂乳制品、全谷物和蔬菜具有高因子负荷。第二种模式与蛋白质摄入量呈正相关，但与钙和钾的摄入量呈负相关，并且对肉、禽、鱼和蛋的因子负荷较高。在调整人体测量学、社会人口学和生活方式因素后，14岁时第一种模式的z评分较高与20岁时的BMD和BMC呈正相关[差异：8.6 mg/cm（2）]。（95% CI：3.0，14.1 mg/cm（2））和21.9 g（95% CI：6.5，37.3 g）]。17岁时相同模式的z评分与20岁时的骨结局无关。14或17岁时的第二种模式与BMD、BMC或骨面积无关。
结论
青春期中期高蛋白质、钙和钾摄入量的饮食模式与20岁时较高的BMD和BMC相关。我们的研究结果表明，青春期大量食用低脂乳制品、全谷物和蔬菜与对骨骼发育的有益影响有关。
BACKGROUND
Relatively little is known about the relations between dietary patterns and bone health in adolescence, which is a period of substantial bone mass accrual.
OBJECTIVES
We derived dietary patterns that were hypothesized to be related to bone health on the basis of their protein, calcium, and potassium contents and investigated their prospective associations with bone mineral density (BMD), bone area, and bone mineral content (BMC) in a cohort of young adults.
DESIGN
The study included 1024 young adults born to mothers who were participating in the Western Australian Pregnancy Cohort (Raine) Study. Dietary information was obtained from food-frequency questionnaires at 14 and 17 y of age. Dietary patterns were characterized according to protein, calcium, and potassium intakes with the use of reduced-rank regression. BMD, bone area, and BMC were estimated with the use of a total body dual-energy X-ray absorptiometry scan at 20 y of age.
RESULTS
We identified 2 major dietary patterns. The first pattern was positively correlated with intakes of protein, calcium, and potassium and had high factor loadings for low-fat dairy products, whole grains, and vegetables. The second pattern was positively correlated with protein intake but negatively correlated with intakes of calcium and potassium and had high factor loadings for meat, poultry, fish, and eggs. After adjustment for anthropometric, sociodemographic, and lifestyle factors, a higher z score for the first pattern at 14 y of age was positively associated with BMD and BMC at 20 y of age [differences: 8.6 mg/cm(2) (95% CI: 3.0, 14.1 mg/cm(2)) and 21.9 g (95% CI: 6.5, 37.3 g), respectively, per SD increase in z score]. The z score for this same pattern at 17 y of age was not associated with bone outcomes at 20 y of age. The second pattern at 14 or 17 y of age was not associated with BMD, BMC, or bone area.
CONCLUSIONS
A dietary pattern characterized by high intakes of protein, calcium, and potassium in midadolescence was associated with higher BMD and BMC at 20 y of age. Our results indicate that high consumption of low-fat dairy products, whole grains, and vegetables in adolescence are associated with beneficial effects on bone development.
影响因子：
7.1
作者：
Wosje, Karen S.;Khoury, Philip R.;Kalkwarf, Heidi J.
通讯作者：
Kalkwarf, Heidi J.
影响因子：
7.1
作者：
Tucker, KL;Chen, HL;Kiel, DP
通讯作者：
Kiel, DP