Spondyloarthropathy as an Old World phenomenon.
Spondyloarthropathy as an Old World phenomenon.
复制标题
脊柱关节病是旧世界的一种现象。
DOI:
10.1016/0049-0172(92)90024-8
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发表时间:
1992
影响因子:
5
通讯作者:
Woods,RJ
中科院分区:
文献类型:
--
作者:
Rothschild,BM;Woods,RJ
The presence of spine and sacroiliac involvement and the nature and distribution of erosive lesions allowed definitive diagnosis of spondyloarthropathy in the great apes (GorillaandPan[chimpanzee]), the lesser ape (Hylobates), and Old World monkeys (Theropithecus, Papio, Cercopithecus, Macaca, Colobus, Presbytis, andErythrocebus). Analysis of lesional character, distribution, radiological appearance, and sex ratios showed a picture indistinguishable from human spondyloarthropathy. This contrasts with orangutans (Pongo), who lack reactive bone or sacroiliac involvement. A different pathophysiology, as yet undefined, is implied for their erosive arthritis. Limited individual susceptibility to spondyloarthropathy in humans (1% to 4%), Old World monkeys (2.4%), and lesser apes (2.4%) contrasts with the high frequency of disease in the great apes (20% to 28%). The wide geographic distribution of this phenomenon suggests an African and perhaps Asian “panendemic.” This natural disease state provides a unique model for in-depth analysis of the contribution of genetic and environmental factors to disease pathophysiology.
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DOI:
--
发表时间:
1986
期刊:
影响因子:
--
作者:
U. Ryan;G. Maxwell
通讯作者:
G. Maxwell
影响因子:
6.5
作者:
S. Streichman;Ela Segal;I. Tatarsky;A. Marmur
通讯作者:
A. Marmur
影响因子:
7.5
作者:
E. Skutelsky;Z. Rudich;D. Danon
通讯作者:
D. Danon
影响因子:
--
作者:
W. Lennarz
通讯作者:
W. Lennarz
影响因子:
5.3
作者:
Bar,RS;Dake,BL;Spanheimer,RG
通讯作者:
Spanheimer,RG