Changes in post-treatment cardiac PET avidity predict overall survival in lung cancer patients treated with chemoradiation: Secondary analysis of the ACRIN 6668/RTOG 0235 clinical trial.
Changes in post-treatment cardiac PET avidity predict overall survival in lung cancer patients treated with chemoradiation: Secondary analysis of the ACRIN 6668/RTOG 0235 clinical trial.
复制标题
DOI:
10.1016/j.radonc.2022.04.003
复制
发表时间:
2022-06
影响因子:
5.7
通讯作者:
Vinogradskiy, Yevgeniy
中科院分区:
文献类型:
--
作者:
Miller, Ryan;Santangelo, Tess;Forghani-Arani, Farnoush;Rusthoven, Chad;Chen, Yingxuan;Castillo, Edward;Castillo, Richard;Guerrero, Thomas;Vinogradskiy, Yevgeniy
The purpose of this work was to use data from a large co-operative group trial to evaluate whether metabolic FDG-PET changes in the heart for lung cancer patients can predict for clinical outcomes. The study found that cardiac SUV changes following definitive chemoradiation are significantly (HR 0.811, 95% CI 0.68–0.96, p = 0.017) associated with overall survival in locally advanced NSCLC patients. If validated in a prospective cohort, our data show the potential for cardiac metabolic changes to be an early predictor for clinical outcomes.
登录
查看更多内容
影响因子:
5.7
作者:
Stam, Barbara;Peulen, Heike;Sonke, Jan-Jakob
通讯作者:
Sonke, Jan-Jakob
DOI:
10.1016/j.ijrobp.2019.12.013
发表时间:
2020-04-01
影响因子:
7
作者:
Vinogradskiy, Yevgeniy;Diot, Quentin;Rusthoven, Chad
通讯作者:
Rusthoven, Chad
DOI:
10.3109/0284186x.2010.521192
发表时间:
2011-01
期刊:
Acta oncologica (Stockholm, Sweden)
影响因子:
--
作者:
Huang EX;Hope AJ;Lindsay PE;Trovo M;El Naqa I;Deasy JO;Bradley JD
通讯作者:
Bradley JD
DOI:
10.1016/j.radonc.2012.04.003
发表时间:
2012-07
期刊:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
影响因子:
--
作者:
McCurdy MR;Castillo R;Martinez J;Al Hallack MN;Lichter J;Zouain N;Guerrero T
通讯作者:
Guerrero T
影响因子:
5.7
作者:
van Dijk,Lisanne V.;Noordzij,Walter;Steenbakkers,Roel J. H. M.
通讯作者:
Steenbakkers,Roel J. H. M.