Th17 cytokines and vaccine-induced immunity.

Th17 cytokines and vaccine-induced immunity.
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DOI:
10.1007/s00281-009-0191-2
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发表时间:
2010-03
影响因子:
9
通讯作者:
Khader, Shabaana A.
Khader, Shabaana A.
中科院分区:
医学1区
文献类型:
--
作者:
Lin, Yinyao;Slight, Samantha R.;Khader, Shabaana A.

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T helper type 17 (Th17) cells are a distinct lineage of T cells that produce the effector molecules IL-17, IL-17F, IL-21 and IL-22. Although the role of Th17 cells in primary immune responses against infections is well documented, there is growing evidence that the Th17 lineage maybe critical for vaccine-induced memory immune responses against infectious diseases. Here we summarize recent progress in our understanding of the role of IL-17 in vaccine-induced immunity.
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