Do myocardial PET–MR and PET–CT FDG images provide comparable information?
Do myocardial PET–MR and PET–CT FDG images provide comparable information?
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心肌 PET-MR 和 PET-CT FDG 图像是否提供可比较的信息？
DOI：
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发表时间：
2016
影响因子：
2.4
通讯作者：
M. Bolen
中科院分区：
文献类型：
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作者：
J. Oldan;Shetal N. Shah;R. Brunken;F. Difilippo;N. Obuchowski;M. Bolen
引言虽然正电子发射断层扫描PET-MR成像正在进入临床实践，这种成像技术的许多方面，如衰减校正尚未得到验证的心肌成像。因此，尚不确定PET-MR FDG图像是否提供与PET-CT FDG图像相当的临床信息。本研究的目的是系统地比较从心脏PET-MR图像获得的相对心肌FDG浓度，从同一天PET-CT images.MethodsMyocardial FDG图像的27例患者进行PET-CT成像，然后PET-MR成像42 ± 13分钟后作为前瞻性肿瘤学研究的一部分进行了分析。平均节段标准化摄取测量（SUVmean），获得在每个17个标准心肌节段和归一化的最亮的segment.ResultsNormalized节段SUVmean值之间没有显着差异的PET-MR和PET-CT图像（平均差异0.002，P = 0.826）。具体的部分是一个轻微的显着预测的差异（P = .057），在前间隔基底segment.ConclusionsPET-MR，相对维斯PET-CT，最大的差异，并没有显着提高节段摄取相对最亮的部分，这表明PET-MR可以使用类似于PET-CT的应用程序中，相对摄取是重要的。
IntroductionAlthough positron emission tomography PET–MR imaging is emerging into clinical practice, many aspects of this imaging technique such as attenuation correction have yet to be validated for myocardial imaging. Thus, it is uncertain whether PET–MR FDG images provide clinical information which is comparable to PET–CT FDG images. The study goal was to systematically compare relative myocardial FDG concentrations obtained from cardiac PET–MR images to those derived from same day PET–CT images.MethodsMyocardial FDG images of 27 patients undergoing PET–CT imaging, followed by PET–MR imaging 42 ± 13 minutes later as part of a prospective oncology study were analyzed. Mean segmental standardized uptake measurements (SUVmean) were obtained in each of the 17 standard myocardial segments and normalized to the brightest segment.ResultsNormalized segmental SUVmean values did not differ significantly between the PET–MR and PET–CT images (mean difference 0.002, P = .826). The specific segment was a marginally significant predictor of the differences (P = .057), with the largest difference in the anteroseptal basal segment.ConclusionsPET–MR, vis-à-vis PET–CT, does not significantly raise segmental uptake relative to the brightest segment, suggesting that PET–MR can be used similarly to PET–CT for applications where relative uptake is important.
影响因子：
19.7
作者：
Schaefer, Juergen F.;Gatidis, Sergios;Schwenzer, Nina F.
通讯作者：
Schwenzer, Nina F.