A case of imatinib-related obstructive bronchiolitis followed long term

A case of imatinib-related obstructive bronchiolitis followed long term
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伊马替尼相关阻塞性细支气管炎长期随访一例

DOI:
10.1016/j.rmcr.2020.101052
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发表时间:
2020
影响因子:
1.1
通讯作者:
Abe Shinji
Abe Shinji
中科院分区:
--
文献类型:
--
作者:
Yajima Chika;Kokuho Nariaki;Toriyama Kazutoshi;Kawagoe Junichiro;Togashi Yuki;Matsubayashi Jun;Nakayama Hideaki;Setoguchi Yasuhiro;Abe Shinji

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阻塞性毛细支气管炎(OB)是一种导致周围细支气管区狭窄和细支气管腔阻塞的顽固性疾病。引起OB的原因是肺和造血干细胞移植、胶原疾病、感染和食物,但很少有药物引起的OB的报道[1]。伊马替尼是一种用于治疗白血病、胃肠道间质瘤等的药物。尽管有一些关于伊马替尼引起的肺损伤作为并发症的报道(Ohnishi等人,2006;Ma等人,2003;Yamasawa等人,2008;Koide等人,2011)[2]、[3]、[4]、[5],但OB尚未见报道。我们遇到了一位与伊马替尼治疗慢性粒细胞白血病有关的OB患者,我们已经跟踪了他10年。药物引起的OB非常罕见,但我们的病例表明,尽管影像上没有阴影,但通过评估有呼吸道症状的患者的肺功能和呼气计算机断层扫描来考虑呼吸道损害的可能性是重要的。
Obstructive bronchiolitis (OB) is an intractable disease causing stenosis in the surrounding bronchiolar region and bronchiolar lumen obstruction. Causes of OB are lung and hematopoietic stem-cell transplantation, collagen diseases, infections, and foods, but there are very few reports of drug-induced OB [1]. Imatinib is a drug used for the treatment of leukemia, gastrointestinal stromal tumors, etc. Although there are some reports of imatinib-induced lung injury as a complication (Ohnishi et al., 2006; Ma et al., 2003; Yamasawa et al., 2008; Koide et al., 2011) [[2], [3], [4], [5]], OB has not been reported. We have encountered a patient with OB related to imatinib administered for chronic myelogenous leukemia, who we have followed for 10 years. Drug-induced OB is very rare, but our case demonstrates the importance of considering the possibility of airway lesions by evaluating pulmonary function and expiratory computed tomography in patients with respiratory symptoms despite no shading on imaging.
两名接受青霉胺治疗的类风湿性关节炎患者出现闭塞性细支气管炎。
DOI: --
发表时间: 1981
影响因子: --
作者:
Kevin C. Murphy;C. Atkins;R. Offer;J. Hogg;H. Stein
通讯作者: H. Stein
DOI: 10.1016/s0140-6736(96)00450-3
发表时间: 1996-07-13
期刊: LANCET
影响因子: 168.9
作者:
Lai, RS;Chiang, AA;Roggli, V
通讯作者: Roggli, V
DOI: --
发表时间: 1949
期刊: British Journal of Industrial Medicine
影响因子: --
作者:
A. Mclaughlin;E. Rogers;K. Dunham
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两名婴儿因吸入婴儿爽身粉而死亡。
DOI: 10.1378/chest.75.4.448
发表时间: 1979
期刊: Chest
影响因子: 9.6
作者:
K. Motomatsu;H. Adachi;T. Uno
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纤维化肺泡炎、闭塞性细支气管炎和柳氮磺吡啶治疗。
DOI: 10.1378/chest.81.6.766
发表时间: 1982
期刊: Chest
影响因子: 9.6
作者:
T. Williams;L. Eidus;P. Thomas
通讯作者: P. Thomas