The effect of a mutagen (N-methyl-N-nitro-N-nitrosoguanidine) on cultured cells from adult Schistosoma japonicum
The effect of a mutagen (N-methyl-N-nitro-N-nitrosoguanidine) on cultured cells from adult Schistosoma japonicum
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诱变剂(N-甲基-N-硝基-N-亚硝基胍)对日本血吸虫成虫培养细胞的影响
DOI:
10.1007/s00436-005-0083-x
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发表时间:
2006-04
影响因子:
2
通讯作者:
Zhong, QP
中科院分区:
文献类型:
--
作者:
Dong, HF;Grevelding, CG;Ming, ZP;Jiang, MS;Zhong, QP
The transforming effect of N-methyl-N-nitro-N-nitrosoguanidine (MNNG) on cultured cells from Schistosoma japonicum (S.japonicum) was studied using mono-factor and orthogonal tests. Under the influence of MNNG, cultured cells grew well, and cell survival time was more than 246 days in low-serum medium. When treated with 3 μg/ml MNNG for 48 h, the number of dividing cells increased significantly as determined by bright-field and scanning electron microscopy (SEM). Under these conditions, abundant microvilli, ruffles, microridges, papillae and blebs were observed on the surface of the induced cells.
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DOI:
--
发表时间:
2001
期刊:
--
影响因子:
--
作者:
Primo Schar
通讯作者:
Primo Schar
DOI:
10.1007/978-981-10-6156-1_91
发表时间:
2018
期刊:
--
影响因子:
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作者:
Y. Okano
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Y. Okano
DOI:
10.1016/b0-08-043152-6/01479-0
发表时间:
2001
期刊:
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影响因子:
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作者:
O. Wells
通讯作者:
O. Wells
影响因子:
2.7
作者:
Dong, HF;Chen, XB;Jiang, MS
通讯作者:
Jiang, MS
DOI:
10.1007/978-3-540-38967-5
发表时间:
1984
期刊:
--
影响因子:
--
作者:
L. Reimer
通讯作者:
L. Reimer