A pilot feasibility study to assess vascularity and perfusion of parathyroid glands using a portable hand-held imager.
A pilot feasibility study to assess vascularity and perfusion of parathyroid glands using a portable hand-held imager.
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DOI：
10.1002/lsm.23478
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发表时间：
2022-03
影响因子：
2.4
通讯作者：
Kim WW
中科院分区：
文献类型：
--
作者：
Oh E;Lee HC;Kim Y;Ning B;Lee SY;Cha J;Kim WW
甲状腺手术中甲状旁腺（PG）的术中定位和保存是一项挑战。一种新的非侵入性技术相结合的近红外PG自体荧光检测和无染料成像血管造影术，允许术中反馈，最近已经推出。本研究的目的是实时评估该技术。一个试点可行性研究的便携式成像设备在四个病人谁接受了甲状腺叶切除术或甲状腺全切除术。在手术过程中，使用实时屏幕显示器监测PG自体荧光和血管分布/组织灌注。进行了三次肺叶切除术和一次甲状腺全切除术。在手术医生识别的9个PG中，使用自体荧光装置确认了8个PG。每个PG被成功地确定为灌注良好或血管离断，并且血管离断的PG被自体移植。初步结果表明，PG自体荧光检测和无染料血管造影术的组合可以潜在地用于评估PG功能。通过进一步的验证研究，可以进一步描述该技术在临床实践中的有效性。
Intraoperative localization and preservation of parathyroid glands (PGs) are challenging during thyroid surgery. A new non-invasive technique of combined near-infrared PG autofluorescence detection and dye-free imaging angiography that allows intraoperative feedback has recently been introduced. The objective of this study was to evaluate this technique in real-time. A pilot feasibility study of a portable imaging device in four patients who underwent either thyroid lobectomy or total thyroidectomy is presented. PG autofluorescence and vascularity/tissue perfusion were monitored using a real-time screen display during the surgical procedure. Three lobectomies and one total thyroidectomy were performed. Among the nine PGs identified by the operating surgeon, eight PGs were confirmed using the autofluorescence device. Each PG was successfully determined to be either well-perfused or devascularized, and devascularized PGs were autotransplanted. The preliminary results suggest that the combination of PG autofluorescence detection and dye-free angiography can potentially be used to assess PG function. With further validation studies, the effectiveness of this technique in clinical practice can be further delineated.
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影响因子：
3.7
作者：
Puzziello, Alessandro;Rosato, Lodovico;De Palma, Maurizio
通讯作者：
De Palma, Maurizio
影响因子：
3.8
作者：
Thomas, Giju;McWade, Melanie A.;Mahadevan-Jansen, Anita
通讯作者：
Mahadevan-Jansen, Anita
影响因子：
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作者：
Solórzano CC;Thomas G;Berber E;Wang TS;Randolph GW;Duh QY;Triponez F
通讯作者：
Triponez F
影响因子：
3.8
作者：
Kose, Emin;Rudin, Anatoliy, V;Berber, Eren
通讯作者：
Berber, Eren
DOI：
10.1007/s00464-016-5330-y
发表时间：
2017-07-01
影响因子：
3.1
作者：
Yu, Hyeong Won;Chung, Joon Woo;Lee, Kyu Eun
通讯作者：
Lee, Kyu Eun