Keratopathy of the rabbit cornea following complete eyelid closure
Keratopathy of the rabbit cornea following complete eyelid closure
复制标题
眼睑完全闭合后兔角膜的角膜病变
DOI：
10.1111/j.1755-3768.1989.tb07102.x
复制
发表时间：
1989
影响因子：
3.4
通讯作者：
K. Kenyon
中科院分区：
文献类型：
--
作者：
J. Koch;M. Refojo;F. Leong;K. Kenyon
本文对46只家兔进行了长达21天的睑板完全缝合术的角膜反应进行了研究。在完全眼睑闭合的前7天，角膜厚度增加了18.4%，糖原减少了32.2%，乳酸增加了27.2%。14天后，角膜厚度急剧增加至89.8%，随后在21天时数值降低，这伴随着广泛的血管化血管翳的形成。这些结果证实了先前的发现，即在闭眼条件下的O2分压基本上低于生理要求，影响内皮泵的能力，并导致主要的角膜肿胀。当在眼睑闭合前即刻配戴硅接触镜时，眼睑闭合后2天的角膜肿胀与未配戴接触镜的眼睛没有差异。
Abstract The corneal response to a complete tarsorrhaphy was studied in 46 rabbits for time periods up to 21 days. During the first 7 days of complete eyelid closure corneal thickness increased up to 18.4%, glycogen decreased 32.2%, and lactate rose 27.2%. A steep increase in corneal thickness to 89.8% appeared after 14 days, followed by decreasing values at 21 days, which was concomitant with the formation of extensive vascularized pannus. These results confirm previous findings that the partial pressure of O2 under closed eye conditions is substantially below physiologic requirements, affects endothelial pump capability, and results in major corneal swelling. When silicone contact lenses were fitted immediately before eyelid closure, corneal swelling 2 days after lid closure did not differ from that in eyes without lenses.
登录
查看更多内容
影响因子：
158.5
作者：
RAVIOLA, E;WIESEL, TN
通讯作者：
WIESEL, TN
氧气在人角膜体内的扩散。
影响因子：
4.4
作者：
Weissman,BA;Fatt,I;Rasson,J
通讯作者：
Rasson,J
影响因子：
4.4
作者：
J. P. Gilbard;S. R. Rossi;K. Gray
通讯作者：
J. P. Gilbard;S. R. Rossi;K. Gray
影响因子：
5.5
作者：
KLYCE, SD
通讯作者：
KLYCE, SD