The association between body mass index class and coronavirus disease 2019 outcomes.
The association between body mass index class and coronavirus disease 2019 outcomes.
复制标题
体重指数等级与2019年冠状病毒病结果之间的关联。
DOI：
10.1038/s41366-020-00721-1
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发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
Lalau JD
中科院分区：
文献类型：
--
作者：
Al-Salameh A;Lanoix JP;Bennis Y;Andrejak C;Brochot E;Deschasse G;Dupont H;Goeb V;Jaureguy M;Lion S;Maizel J;Moyet J;Vaysse B;Desailloud R;Ganry O;Schmit JL;Lalau JD
越来越多的数据表明，肥胖会影响冠状病毒病2019年(新冠肺炎)。我们研究的主要目标是评估体重指数类别和新冠肺炎危重类型之间的关系。对在亚眠大学医院(亚眠，法国)连续住院的经实验室确认的新冠肺炎成人患者的数据进行了回顾性提取。在Logistic回归分析中，探讨了体重指数类别和复合主要终点(住进重症监护病房或死亡)之间的关系。总共纳入了433名患者，可获得329年的BMI数据：20名体重过轻(6.1%)，95名正常体重(28.9%)，90名超重(27.4%)，124名肥胖(37.7%)。在完全调整的模型中，BMI类别与主要终点相关；超重和肥胖的优势比(OR)[95%可信区间(CI)]分别为1.58[0.77-3.24]和2.58[1.28-5.31]。在完全调整的模型中，超重(3.16[1.29-8.06])和肥胖(3.05[1.25-7.82])入院ICU的OR[95%CI]相似。在所有BMI类别中，未调整的死亡OR是相似的，而肥胖只与调整后的更高风险相关。我们的结果表明，超重(不仅仅是肥胖)与ICU入院有关，但超重与死亡无关。
A growing body of data suggests that obesity influences coronavirus disease 2019 (COVID-19). Our study’s primary objective was to assess the association between body mass index (BMI) categories and critical forms of COVID-19. Data on consecutive adult patients hospitalized with laboratory-confirmed COVID-19 at Amiens University Hospital (Amiens, France) were extracted retrospectively. The association between BMI categories and the composite primary endpoint (admission to the intensive care unit or death) was probed in a logistic regression analysis. In total, 433 patients were included, and BMI data were available for 329: 20 were underweight (6.1%), 95 have a normal weight (28.9%), 90 were overweight (27.4%), and 124 were obese (37.7%). The BMI category was associated with the primary endpoint in the fully adjusted model; the odds ratio (OR) [95% confidence interval (CI)] for overweight and obesity were respectively 1.58 [0.77–3.24] and 2.58 [1.28–5.31]. The ORs [95% CI] for ICU admission were similar for overweight (3.16 [1.29–8.06]) and obesity (3.05 [1.25–7.82]) in the fully adjusted model. The unadjusted ORs for death were similar in all BMI categories while obesity only was associated with higher risk after adjustment. Our results suggest that overweight (and not only obesity) is associated with ICU admission, but overweight is not associated with death.
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DOI：
10.15585/mmwr.mm6915e3
发表时间：
2020-04-17
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Garg S;Kim L;Whitaker M;O'Halloran A;Cummings C;Holstein R;Prill M;Chai SJ;Kirley PD;Alden NB;Kawasaki B;Yousey-Hindes K;Niccolai L;Anderson EJ;Openo KP;Weigel A;Monroe ML;Ryan P;Henderson J;Kim S;Como-Sabetti K;Lynfield R;Sosin D;Torres S;Muse A;Bennett NM;Billing L;Sutton M;West N;Schaffner W;Talbot HK;Aquino C;George A;Budd A;Brammer L;Langley G;Hall AJ;Fry A
通讯作者：
Fry A
急性呼吸窘迫综合征中的“肥胖悖论”：Asystematic Resectic和Meta-Analysis。
影响因子：
3.7
作者：
Zhi G;Xin W;Ying W;Guohong X;Shuying L
通讯作者：
Shuying L
影响因子：
9.3
作者：
Nie W;Zhang Y;Jee SH;Jung KJ;Li B;Xiu Q
通讯作者：
Xiu Q
DOI：
10.1001/jama.2020.6775
发表时间：
2020-01-01
期刊：
JAMA, Journal of the American Medical Association
影响因子：
--
作者：
Richardson, Safiya;Hirsch, Jamie S.;,
通讯作者：
,
影响因子：
105.7
作者：
Docherty, Annemarie B.;Harrison, Ewen M.;Semple, Malcolm G.
通讯作者：
Semple, Malcolm G.