Geometry, time-dependent and failure properties of human meniscal attachments.
Geometry, time-dependent and failure properties of human meniscal attachments.
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DOI：
10.1016/j.jbiomech.2009.09.043
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发表时间：
2010-02-10
影响因子：
2.4
通讯作者：
Donahue, Tammy L. Haut
中科院分区：
文献类型：
--
作者：
Hauch, Karen N.;Villegas, Diego F.;Donahue, Tammy L. Haut
半月板切除术已被证明会导致骨关节炎，而半月板置换术的成功率仍然值得怀疑。有人认为，髋臼置换术的成功取决于几个因素，其中之一是置换物在角位置与胫骨平台的牢固固定和牢固连接。为了帮助开发人工耳蜗替代物，本研究的目的是确定人类人工耳蜗附件的时间依赖性和失效特性。与时间依赖性试验相反，在单轴失效试验期间，使用电荷耦合摄像机记录附件表面的局部应变和线性模量分布。外侧附件的横截面积在统计学上小于内侧附件，且长于内侧附件。前附着体在统计学上比后附着体更长，横截面积更小。从应力松弛测试来看，内侧前附着体的载荷和应力松弛率在统计学上大于内侧后附着体。不同附着体之间的蠕变、结构特性或极限应力没有显著差异。不同附件之间以及附件沿着长度方向的极限应变不同。半月板区域（10.4±6.9%）和中间物质区域（12.7±16.4%）的极限应变小于骨插入区域（32.2±21.5%）。还发现外侧和前部附件的应变分别大于内侧和后部附件，具有统计学意义。与半月板区域（153±123 MPa）和中间物质区域（195±121 MPa）相比，骨插入区域（69.7±33.7 MPa）的线性模量在统计学上较弱。总体而言，前部附件（169±130 MPa）在统计学上也强于后部附件（90.8±64.9 MPa）。这些结果可用于帮助设计组织工程替代支架及其插入物，并显示附着体之间以及附着体内部材料特性的差异。
Meniscectomies have been shown to lead to osteoarthritis and the success of meniscal replacements remains questionable. It has been suggested that the success of a meniscal replacement is dependent on several factors, one of which is the secure fixation and firm attachment of the replacement to the tibial plateau at the horn locations. To aid in the development of meniscal replacements, the objectives of the current study were to determine the time-dependent and failure properties of human meniscal attachments. In contrast to the time-dependent tests, during uniaxial failure testing a charge-coupled video camera was used to document the local strain and linear modulus distribution across the surface of the attachments. The lateral attachments were statistically smaller in cross-sectional area and longer than the medial attachments. The anterior attachments were statistically longer and had a smaller cross-sectional area than the posterior attachments. From the stress relaxation tests, the load and stress relaxation rates of the medial anterior attachment were statistically greater than the medial posterior attachment. There were no significant differences in the creep, structural properties or the ultimate stress between the different attachments. Ultimate strain varied between attachments as well as along the length of the attachment. Ultimate strain in the meniscus region (10.4±6.9%) and mid-substance region (12.7±16.4%) was smaller than the bony insertion region (32.2±21.5%). The lateral and anterior attachments were also found to have statistically greater strain than the medial and posterior attachments, respectively. The linear modulus was statistically weaker in the bony insertion region (69.7±33.7 MPa) compared to the meniscus region (153±123 MPa) and mid-substance region (195±121 MPa). Overall the anterior attachments (169±130 MPa) were also found to be statistically stronger than the posterior attachments (90.8±64.9 MPa). These results can be used to help design tissue engineered replacement menisci and their insertions and show the differences in material properties between attachment as well as within an attachment.
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DOI：
10.1115/1.1351889
发表时间：
2001-04-01
影响因子：
1.7
作者：
Donahue, TLH;Gregersen, C;Howell, SM
通讯作者：
Howell, SM
影响因子：
2.4
作者：
Race, A;Amis, AA
通讯作者：
Amis, AA
影响因子：
3.8
作者：
Choi, Nam-Hong;Son, Kyung-Mo;Victoroff, Brian N.
通讯作者：
Victoroff, Brian N.
影响因子：
4.8
作者：
LaPrade, RF;Bollom, TS;Meister, K
通讯作者：
Meister, K
影响因子：
5
作者：
De Smet, Arthur A.;Blankenbaker, Donna G.;Shinki, Kazuhiko
通讯作者：
Shinki, Kazuhiko