Improving the pharmacologic management of pain in older adults: identifying the research gaps and methods to address them.
Improving the pharmacologic management of pain in older adults: identifying the research gaps and methods to address them.
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DOI：
10.1111/j.1526-4637.2011.01211.x
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发表时间：
2011-09
期刊：
影响因子：
--
通讯作者：
Zacharoff KL
中科院分区：
文献类型：
--
作者：
Reid MC;Bennett DA;Chen WG;Eldadah BA;Farrar JT;Ferrell B;Gallagher RM;Hanlon JT;Herr K;Horn SD;Inturrisi CE;Lemtouni S;Lin YW;Michaud K;Morrison RS;Neogi T;Porter LL;Solomon DH;Von Korff M;Weiss K;Witter J;Zacharoff KL
越来越多的人认识到需要更好的药物治疗老年人慢性疼痛。为了解决这一需求，美国国立卫生研究院疼痛联盟于2010年9月发起了“老年人慢性疼痛药理管理专家小组讨论”会议，以确定研究差距和解决这些问题的策略。由于阿片类药物和非甾体抗炎药物的风险和益处仍然存在不确定性，因此特别强调确定阿片类药物和非甾体抗炎药物使用方面的差距。18名小组成员作了口头报告；每次会议之后都有一个多学科小组讨论。对会议记录和小组成员的幻灯片演示进行了审查，以确定差距，以及小组成员建议的研究类型和研究方法可以最好地解决这些差距。在治疗领域确定了15个差距(例如：例如，常用镇痛药的长期安全性和有效性的不确定性)、流行病学（例如，缺乏对常见疼痛综合征病程的了解）和实施(例如：对将循证疼痛治疗转化为实践的最佳策略的理解有限)。对来自电子卫生保健数据库、观察性队列研究和正在进行的队列研究（增加了疼痛和其他相关结果测量）的数据进行分析，被认为是建立适合年龄的证据基础的实用方法，可以改善晚年疼痛的药理学管理。专家小组认为，解决当前报告中提出的差距对于改善患有慢性疼痛的老年人的健康和福祉具有巨大潜力。
There has been a growing recognition of the need for better pharmacologic management of chronic pain among older adults. To address this need, the National Institutes of Health Pain Consortium sponsored an “Expert Panel Discussion on the Pharmacological Management of Chronic Pain in Older Adults” conference in September, 2010, to identify research gaps and strategies to address them. Specific emphasis was placed on ascertaining gaps regarding use of opioid and non-steroidal anti-inflammatory medications because of continued uncertainties regarding their risks and benefits. Eighteen panel members provided oral presentations; each was followed by a multidisciplinary panel discussion. Meeting transcripts and panelists’ slide presentations were reviewed to identify the gaps, and the types of studies and research methods panelists suggested could best address them. Fifteen gaps were identified in the areas of treatment(e.g., uncertainty regarding the long-term safety and efficacy of commonly prescribed analgesics), epidemiology (e.g., lack of knowledge regarding the course of common pain syndromes), and implementation(e.g., limited understanding of optimal strategies to translate evidence-based pain treatments into practice). Analyses of data from electronic health care databases, observational cohort studies, and ongoing cohort studies (augmented with pain and other relevant outcomes measures) were felt to be practical methods for building an age-appropriate evidence base to improve the pharmacologic management of pain in later life. Addressing the gaps presented in the current report was judged by the panel to have substantial potential to improve the health and well being of older adults with chronic pain.
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DOI：
10.1016/j.jpain.2008.10.008
发表时间：
2009-02
期刊：
The journal of pain
影响因子：
--
作者：
Chou R;Fanciullo GJ;Fine PG;Adler JA;Ballantyne JC;Davies P;Donovan MI;Fishbain DA;Foley KM;Fudin J;Gilson AM;Kelter A;Mauskop A;O'Connor PG;Passik SD;Pasternak GW;Portenoy RK;Rich BA;Roberts RG;Todd KH;Miaskowski C;American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
通讯作者：
American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
影响因子：
4
作者：
Chapman, C. Richard;Lipschitz, David L.;Weisner, Constance M.
通讯作者：
Weisner, Constance M.
DOI：
10.1093/gerona/62.9.989
发表时间：
2007-09-01
影响因子：
5.1
作者：
Bryan, Lucinda L.;Grigsby, Jim;Baxter, Judith
通讯作者：
Baxter, Judith
DOI：
10.1111/j.1532-5415.2004.52174.x
发表时间：
2004-04-01
影响因子：
6.3
作者：
Ferrucci, L;Guralnik, JM;Walston, JD
通讯作者：
Walston, JD
影响因子：
120.7
作者：
EVANS, DA;FUNKENSTEIN, H;TAYLOR, JO
通讯作者：
TAYLOR, JO