Intact but less accessible phonetic representations in adults with dyslexia.
Intact but less accessible phonetic representations in adults with dyslexia.
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DOI:
10.1126/science.1244333
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发表时间:
2013-12-06
期刊:
影响因子:
--
通讯作者:
Ghesquière P
中科院分区:
文献类型:
--
作者:
Boets B;Op de Beeck HP;Vandermosten M;Scott SK;Gillebert CR;Mantini D;Bulthé J;Sunaert S;Wouters J;Ghesquière P
Dyslexia is a severe and persistent reading and spelling disorder caused by impairment to manipulate speech sounds. Here, we combine functional magnetic resonance brain imaging with multi-voxel pattern analysis and functional and structural connectivity analysis to disentangle whether dyslexics’ phonological deficits are caused by poor quality of the phonetic representations or by difficulties in accessing intact phonetic representations. We show that phonetic representations are hosted bilaterally in primary and secondary auditory cortices, and that their neural quality is intact in adults with dyslexia. However, the functional and structural connectivity between bilateral auditory cortices and left inferior frontal gyrus (a region involved in higher-level phonological processing) is significantly hampered in dyslexics, suggesting deficient access to otherwise intact phonetic representations.
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期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
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The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
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