Dementia Associated with the Acquired Immunodeficiency Syndrome

Dementia Associated with the Acquired Immunodeficiency Syndrome
复制标题

与获得性免疫缺陷综合征相关的痴呆

DOI:
10.1056/nejm199504063321407
复制
发表时间:
1995
期刊:
The New England Journal of Medicine
影响因子:
--
通讯作者:
H. Gendelman
H. Gendelman
中科院分区:
--
文献类型:
--
作者:
S. Lipton;H. Gendelman

文献摘要

参考文献

被引文献

相似文献

大约三分之一患有获得性免疫缺陷综合症(艾滋病)的成年人和一半的儿童最终会出现神经系统并发症,这些并发症直接可归因于人类免疫缺陷病毒1型(HIV-1)对大脑的感染。1、2即使在没有机会性感染或继发性癌症的情况下,也会出现神经系统问题。3重要的临床表现包括精神集中受损、手运动缓慢和行走困难。这种疾病被普赖斯和他的同事称为艾滋病痴呆症复合体3;一个较新的术语是与HIV-1相关的认知运动复合体。从病理上讲,HIV-1在中枢神经系统(或称HIV……)感染的迹象。
Approximately one third of adults and half of children with the acquired immunodeficiency syndrome (AIDS) eventually have neurologic complications, which are directly attributable to infection of the brain by the human immunodeficiency virus type 1 (HIV-1).1,2 Neurologic problems occur even in the absence of opportunistic infection or secondary cancer.3 Important clinical manifestations include impaired mental concentration, slowness of hand movements, and difficulty in walking. This malady has been called the AIDS dementia complex by Price and colleagues3; a more recent term is HIV-1–associated cognitive–motor complex. Pathologically, the signs of HIV-1 infection in the central nervous system (or HIV . . .
DOI: 10.1097/00001756-199210000-00023
发表时间: 1992-10-01
期刊: NEUROREPORT
影响因子: 1.7
作者:
LIPTON, SA
通讯作者: LIPTON, SA
用 IL-1-β、肿瘤坏死因子或 IFN-γ 刺激的人单核细胞合成双相血小板激活因子。
DOI: --
发表时间: 1988
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Valone,FH;Epstein,LB
通讯作者: Epstein,LB
DOI: 10.1073/pnas.88.14.6368
发表时间: 1991-07-01
影响因子: 11.1
作者:
DAWSON, VL;DAWSON, TM;SNYDER, SH
通讯作者: SNYDER, SH
DOI: 10.4049/jimmunol.144.1.129
发表时间: 1990-01
影响因子: 4.4
作者:
K. Selmaj;M. Farooq;W. T. Norton;C. Raine;C. Brosnan
通讯作者: K. Selmaj;M. Farooq;W. T. Norton;C. Raine;C. Brosnan
DOI: 10.1126/science.2326646
发表时间: 1990-04-20
期刊: SCIENCE
影响因子: 56.9
作者:
DREYER, EB;KAISER, PK;LIPTON, SA
通讯作者: LIPTON, SA