The spine in Paget's disease.
The spine in Paget's disease.
复制标题
DOI：
10.1007/s00256-006-0270-6
复制
发表时间：
2007-07
影响因子：
2.1
通讯作者：
Tyrrell, P. N. M.
中科院分区：
文献类型：
--
作者：
Dell'Atti, C.;Cassar-Pullicino, V. N.;Lalam, R. K.;Tins, B. J.;Tyrrell, P. N. M.
佩吉特病（PD）是一种慢性代谢活性骨疾病，其特征在于由于成骨细胞和成骨细胞活性增加而引起的骨建模和重建障碍。脊椎是第二个最常见的受影响的网站。本文综述了各种脊柱病理机制和骨动力学参与产生的各种影像学表现及其临床意义。先进的成像的骨，关节和骨髓表现的PD在所有的脊椎组件。脊椎的改变通常会导致包括背痛、椎管狭窄和神经功能障碍在内的临床症状。由于PD累及导致的各种病理并发症导致这些临床症状。认识到脊髓PD的影像学表现和导致临床症状的潜在并发症，可以在适当的治疗之前对患者进行准确的评估。
Paget’s disease (PD) is a chronic metabolically active bone disease, characterized by a disturbance in bone modelling and remodelling due to an increase in osteoblastic and osteoclastic activity. The vertebra is the second most commonly affected site. This article reviews the various spinal pathomechanisms and osseous dynamics involved in producing the varied imaging appearances and their clinical relevance. Advanced imaging of osseous, articular and bone marrow manifestations of PD in all the vertebral components are presented. Pagetic changes often result in clinical symptoms including back pain, spinal stenosis and neural dysfunction. Various pathological complications due to PD involvement result in these clinical symptoms. Recognition of the imaging manifestations of spinal PD and the potential complications that cause the clinical symptoms enables accurate assessment of patients prior to appropriate management.
登录
查看更多内容
影响因子：
--
作者：
ALTMAN, RD
通讯作者：
ALTMAN, RD
影响因子：
6.2
作者：
Cooper, C;Schafheutle, K;Barker, D
通讯作者：
Barker, D
影响因子：
4.2
作者：
Cundy, HR;Gamble, G;Cundy, T
通讯作者：
Cundy, T
影响因子：
19.7
作者：
Graham, TS
通讯作者：
Graham, TS
影响因子：
2.6
作者：
GUYER, PB;SHEPHERD, DFC
通讯作者：
SHEPHERD, DFC