Tuck-in Lamellar keratoplasty with an lenticule obtained by small incision lenticule extraction for treatment of Post- LASIK Ectasia.
Tuck-in Lamellar keratoplasty with an lenticule obtained by small incision lenticule extraction for treatment of Post- LASIK Ectasia.
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DOI：
10.1038/s41598-017-18201-4
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发表时间：
2017-12-19
影响因子：
4.6
通讯作者：
Lu TC
中科院分区：
文献类型：
--
作者：
Jiang Y;Li Y;Yang S;Lu TC
角膜扩张症是LASIK术后罕见但严重的并发症。我们的主要目的是描述和评价利用SILE获得的晶状体的嵌入性板层角膜移植治疗LASIK术后扩张的有效性和安全性。对3例(3只眼)准分子激光原位角膜磨镶术后中央角膜厚度小于4 0 0 µm的角膜扩张症患者进行板层角膜移植，术后随访至少12个月。我们在手术前后测量的主要结果包括：眼前节光学相干断层扫描(AS-OCT)、角膜地形图和裂隙灯显微镜监测。术前、术后1 、1个月、3个月、12个月平均角膜总厚度分别为360.00 ± 32.07 、590.00 ± 10.00 、536.67 ± 11.54 、523.33 ± 37.85 、466.67 ± 41.63 ，术后1 、1个月、3个月、12个月晶状体植入数分别为173.33 ± 41.63 、136.67 ± 25.16 µm。133.33 ± 40.41 微米，130.00 ± 17.32 微米，无免疫排斥或其他并发症发生。对于LASIK术后角膜扩张症，尤其是角膜厚度<400 μm的重症患者，采用微笑获得晶状体的板层角膜移植是一种安全的、可供选择的手术方法。
Corneal ectasia is a rare but serious post-operative complication of LASIK. Our main aim was to describe and evaluate the efficacy and safety of tuck-in lamellar keratoplasty with an lenticule obtained by SMILE for treatment of Post LASIK Ectasia. Tuck-in lamellar keratoplasty was performed on three post-LASIK cornea ectasia patients (three eyes) with central corneal thickness less than 400 µm. Each patient was monitored for at least 12 months. Our primary outcomes measured pre and post-operatively included: Anterior segment optical coherence tomography(AS-OCT), corneal topography and monitored by slit-lamp microscopy. The mean total corneal thickness preoperatively and 1 day, 1 month, 3 months and 12 months post-op were 360.00 ± 32.07 µm, 590.00 ± 10.00 µm, 536.67 ± 11.54 µm, 523.33 ± 37.85 µm, 466.67 ± 41.63 µm. The mean lenticule implanted 1 day, 1 month, 3 months and 12 months post-op were 173.33 ± 41.63 µm,136.67 ± 25.16 µm, 133.33 ± 40.41 µm, 130.00 ± 17.32 µm. There was no evidence of immune rejection or other complications. Tuck-in lamellar keratoplasty with an lenticule obtained by SMILE seems to be a safe and alternative surgical approach in the treatment of post - LASIK cornea ectasia, especially for severe cases with cornea thickness less than 400 μm.
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