Social Media Interventions to Promote HIV Testing, Linkage, Adherence, and Retention: Systematic Review and Meta-Analysis.

Social Media Interventions to Promote HIV Testing, Linkage, Adherence, and Retention: Systematic Review and Meta-Analysis.
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DOI:
10.2196/jmir.7997
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发表时间:
2017-11-24
影响因子:
7.4
通讯作者:
Tucker JD
Tucker JD
中科院分区:
医学2区
文献类型:
--
作者:
Cao B;Gupta S;Wang J;Hightow-Weidman LB;Muessig KE;Tang W;Pan S;Pendse R;Tucker JD

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社交媒体越来越多地用于为全球重点人群提供艾滋病毒干预措施。然而,人们对社交媒体对人类免疫缺陷病毒(HIV)干预措施的具体用途和影响知之甚少。本系统综述考察了社交媒体干预措施在促进关键人群中艾滋病毒检测、联系、依从性和保留方面的有效性。我们使用系统评价和荟萃分析首选报告项目 (PRISMA) 检查表和 Cochrane 指南进行本次评价,并将其注册到国际系统评价前瞻性登记册 PROSPERO 上。我们使用与艾滋病毒、社交媒体和关键人群相关的搜索词系统地搜索了六个数据库和三个会议网站。我们纳入的研究包括:(1) 在社交媒体平台上创建或实施干预措施,(2) 研究人群包括男男性行为者 (MSM)、跨性别者、注射吸毒者 (PWID) 和/或性工作者,(3) 结果包括促进 HIV 检测、联系、依从性和/或保留。 Meta 分析由 Review Manager 5.3 版进行。通过随机效应模型计算汇总相对风险 (RR) 和 95% 置信区间。在确定的 981 份手​​稿中,26 项研究符合纳入标准。我们发现 18 项研究来自高收入国家,8 项来自中等收入国家,0 项来自低收入国家。 8 项是随机对照试验,18 项是观察性研究。所有研究 (n=26) 均包括 MSM;五项研究还包括跨性别者。 21 项研究的重点是 HIV 检测,其中 4 项研究关注 HIV 检测和与护理的联系,1 项研究关注抗逆转录病毒治疗的依从性。社交媒体干预措施用于执行以下任务:建立在线互动社区以鼓励艾滋病毒检测/依从性(10 项研究)、提供艾滋病毒检测服务(9 项研究)、传播艾滋病毒信息(9 项研究)以及开发干预材料(1 项研究)。在提供艾滋病毒自我检测的研究中,16%的参与者从社交媒体平台请求艾滋病毒检测试剂盒。 Facebook (n=15) 和同性恋约会应用程序 Grindr (n=10) 等现有社交媒体平台使用频率最高。四项研究的数据显示,社交媒体干预后,艾滋病毒检测率有所增加(n=1283,RR 1.50,95% CI 1.28-1.76)。在社交媒体干预为参与性的研究中,干预组的 HIV 检测率高于对照组(n=1023,RR 1.64,95% CI 1.19-2.26)。在许多情况下,社交媒体干预措施可以有效促进男男性行为者的艾滋病毒检测。在低收入和中等收入国家以及其他重点人群中,除了艾滋病毒检测之外,还需要考虑通过社交媒体干预措施来改善艾滋病毒服务。国际前瞻性系统评价登记册(PROSPERO):CRD42016048073; http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42016048073(由 WebCite 存档,网址为 http://www.webitation.org/6usLCJK3v)
Social media is increasingly used to deliver HIV interventions for key populations worldwide. However, little is known about the specific uses and effects of social media on human immunodeficiency virus (HIV) interventions. This systematic review examines the effectiveness of social media interventions to promote HIV testing, linkage, adherence, and retention among key populations. We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist and Cochrane guidelines for this review and registered it on the International Prospective Register of Systematic Reviews, PROSPERO. We systematically searched six databases and three conference websites using search terms related to HIV, social media, and key populations. We included studies where (1) the intervention was created or implemented on social media platforms, (2) study population included men who have sex with men (MSM), transgender individuals, people who inject drugs (PWID), and/or sex workers, and (3) outcomes included promoting HIV testing, linkage, adherence, and/or retention. Meta-analyses were conducted by Review Manager, version 5.3. Pooled relative risk (RR) and 95% confidence intervals were calculated by random-effects models. Among 981 manuscripts identified, 26 studies met the inclusion criteria. We found 18 studies from high-income countries, 8 in middle-income countries, and 0 in low-income countries. Eight were randomized controlled trials, and 18 were observational studies. All studies (n=26) included MSM; five studies also included transgender individuals. The focus of 21 studies was HIV testing, four on HIV testing and linkage to care, and one on antiretroviral therapy adherence. Social media interventions were used to do the following: build online interactive communities to encourage HIV testing/adherence (10 studies), provide HIV testing services (9 studies), disseminate HIV information (9 studies), and develop intervention materials (1 study). Of the studies providing HIV self-testing, 16% of participants requested HIV testing kits from social media platforms. Existing social media platforms such as Facebook (n=15) and the gay dating app Grindr (n=10) were used most frequently. Data from four studies show that HIV testing uptake increased after social media interventions (n=1283, RR 1.50, 95% CI 1.28-1.76). In the studies where social media interventions were participatory, HIV testing uptake was higher in the intervention arm than the comparison arm (n=1023, RR 1.64, 95% CI 1.19-2.26). Social media interventions are effective in promoting HIV testing among MSM in many settings. Social media interventions to improve HIV services beyond HIV testing in low- and middle-income countries and among other key populations need to be considered. International Prospective Register of Systematic Reviews (PROSPERO): CRD42016048073; http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42016048073 (Archived by WebCite at http://www. webcitation.org/6usLCJK3v)
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