Prevalence of diabetes mellitus in outpatients with essential hypertension in China: a cross-sectional study.
Prevalence of diabetes mellitus in outpatients with essential hypertension in China: a cross-sectional study.
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DOI：
10.1136/bmjopen-2013-003798
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发表时间：
2013-11-20
期刊：
影响因子：
2.9
通讯作者：
Wang W
中科院分区：
文献类型：
--
作者：
Liu J;Zhao D;Liu J;Qi Y;Sun J;Wang W
目的探讨中国门诊高血压患者中糖尿病（DM）的患病率及空腹血糖（FPG）和2小时血糖（2-hPG）新发现DM的情况。 多中心横断面研究。中国46家医院研究对象于2009年6月至12月在中国22个省、自治区和直辖市的46家医院的高血压门诊连续招募。每家医院至少招募100名连续患者。所有患者均测量FPG，无DM病史者测量2-hPG。共纳入4942例年龄≥20岁的高血压门诊患者。 糖尿病患病率为24.3%（包括既往和新诊断病例）。在1202例糖尿病患者中，417例（34.7%）为新发现。在年龄<45岁的患者中，52.6%的DM病例是新发现的。 在417例新发现的糖尿病患者中，54.9%通过FPG检测确定，其余45.1%通过2-hPG检测确定; 27.1%的新发现的糖尿病患者FPG <6.1 mmol/L，16.5% FPG <5.6 mmol/L。 在≥65岁的老年患者中，32.4%的患者FPG正常（<6.1 mmol/L），24.5%的患者FPG最佳（<5.6 mmol/L）。 我们的研究结果显示中国高血压门诊患者中糖尿病和新发现糖尿病的患病率很高。在FPG检测基础上增加2-hPG检测可提高糖尿病的检出率，尤其是老年患者。
To investigate the prevalence of diabetes mellitus (DM) and new detection of DM using fasting plasma glucose (FPG) and 2 h plasma glucose (2-hPG) in hypertensive outpatients in China. Multicenter cross-sectional study. 46 hospitals in China. Study patients were consecutively recruited from June to December 2009 from hypertension outpatient clinics in 46 hospitals in 22 provinces, autonomous regions and municipalities in China. At least 100 consecutive patients were recruited in each hospital. FPG was measured for all patients and 2-hPG was measured in those without a history of DM. A total of 4942 hypertensive outpatients aged ≥20 years were included. Prevalence of DM was 24.3% (which included both previously and newly diagnosed cases). Among the 1202 patients with DM, 417 (34.7%) were newly detected. In patients aged <45 years, 52.6% of cases of DM were newly detected. Of the 417 cases of newly detected diabetes, 54.9% were identified using FPG tests and the remaining 45.1% by 2-hPG tests; 27.1% of patients with newly detected DM had FPG <6.1 mmol/L and 16.5% had FPG <5.6 mmol/L. Among the elderly patients (≥65 years), 32.4% had normal FPG (<6.1 mmol/L) and 24.5% had optimal FPG (<5.6 mmol/L). Our findings showed a high prevalence of DM and newly detected DM among Chinese hypertensive outpatients. Application of additional 2-hPG testing to FPG assay can improve the detection rate of DM, especially in elderly patients.
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