Suppressed recombination and a pairing anomaly on the mating-type chromosome of Neurospora tetrasperma.
Suppressed recombination and a pairing anomaly on the mating-type chromosome of Neurospora tetrasperma.
复制标题
四子脉脉孢菌交配型染色体上的重组被抑制和配对异常。
DOI:
10.1093/genetics/154.2.623
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发表时间:
2000
期刊:
影响因子:
3.3
通讯作者:
Natvig,DO
中科院分区:
文献类型:
--
作者:
Gallegos,A;Jacobson,DJ;Raju,NB;Skupski,MP;Natvig,DO
Neurospora crassa and related heterothallic ascomycetes produce eight homokaryotic self-sterile ascospores per ascus. In contrast, asci of N. tetrasperma contain four self-fertile ascospores each with nuclei of both mating types (matA and mata). The self-fertile ascospores of N. tetrasperma result from first-division segregation of mating type and nuclear spindle overlap at the second meiotic division and at a subsequent mitotic division. Recently,Merinoet al. presented population-genetic evidence that crossing over is suppressed on the mating-type chromosome of N. tetrasperma, thereby preventing second-division segregation of mating type and the formation of self-sterile ascospores. The present study experimentally confirmed suppressed crossing over for a large segment of the mating-type chromosome by examining segregation of markers in crosses of wild strains. Surprisingly, our study also revealed a region on the far left arm where recombination is obligatory. In cytological studies, we demonstrated that suppressed recombination correlates with an extensive unpaired region at pachytene. Taken together, these results suggest an unpaired region adjacent to one or more paired regions, analogous to the nonpairing and pseudoautosomal regions of animal sex chromosomes. The observed pairing and obligate crossover likely reflect mechanisms to ensure chromosome disjunction.
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影响因子:
5.2
作者:
Malapit CA;Caldwell DR;Sassu N;Milbin S;Howell AR
通讯作者:
Howell AR
DOI:
10.1002/dvg.1020150111
发表时间:
1994-01-01
期刊:
DEVELOPMENTAL GENETICS
影响因子:
--
作者:
RAJU, NB;PERKINS, DD
通讯作者:
PERKINS, DD
DOI:
10.1016/s0074-7696(08)62200-7
发表时间:
1994
期刊:
International review of cytology
影响因子:
--
作者:
J. Graves;J. W. Foster
通讯作者:
J. W. Foster
DOI:
10.4148/1941-4765.1507
发表时间:
1988
期刊:
Fungal Genetics Reports
影响因子:
--
作者:
R. L. Metzenberg;J. Grotelueschen
通讯作者:
J. Grotelueschen
影响因子:
3.3
作者:
Merino,ST;Nelson,MA;Jacobson,DJ;Natvig,DO
通讯作者:
Natvig,DO