Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives.

Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives.
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DOI:
10.1039/c0cc04754f
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发表时间:
2011-01-07
期刊:
Chemical communications (Cambridge, England)
影响因子:
--
通讯作者:
Wilson AJ
Wilson AJ
中科院分区:
其他
文献类型:
--
作者:
Filby MH;Muldoon J;Dabb S;Fletcher NC;Ashcroft AE;Wilson AJ

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Fac and mer isomers of functionalised ruthenium(ii) tris(bipyridine) derivatives are shown to have different recognition properties towards cytochrome c. This manuscript illustrates that the geometric arrangement of protein-binding groups around a ruthenium(ii) core leads to dramatic differences in cytochrome c (cyt c) binding highlighting that it is possible to define synthetic receptors with shape complementarity to protein surfaces.
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