Pre-diagnosis diet and survival after a diagnosis of ovarian cancer.
Pre-diagnosis diet and survival after a diagnosis of ovarian cancer.
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DOI：
10.1038/bjc.2017.120
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发表时间：
2017-06-06
影响因子：
8.8
通讯作者：
Webb PM
中科院分区：
文献类型：
--
作者：
Playdon MC;Nagle CM;Ibiebele TI;Ferrucci LM;Protani MM;Carter J;Hyde SE;Neesham D;Nicklin JL;Mayne ST;Webb PM
由于研究数量有限和结果不一致，饮食与卵巢癌诊断后生存率之间的关系尚不清楚。我们研究了2002年至2005年诊断为浸润性上皮性卵巢癌的澳大利亚女性人群队列（n=811）中诊断前饮食与总生存率之间的关系。饮食通过验证的食物频率问卷进行测量。截至2014年8月31日，通过医疗记录审查和澳大利亚国家死亡指数联系确定了死亡人数。我们进行了考克斯比例风险回归分析，控制了诊断年龄、肿瘤分期、分级和亚型、残留疾病、吸烟状况、体重指数、体力活动、婚姻状况和能量摄入。我们观察到，与最低四分位数的纤维摄入量相比，最高四分位数的纤维摄入量改善了生存率（风险比（HR）=0.69，95% CI：0.53-0.90，P趋势=0.002）。与最低摄入量的绿色叶菜类相比，最高摄入量的女性生存率更高（HR=0.79，95% CI：0.62-0.99），鱼类（HR=0.74，95% CI：0.57-0.95），多不饱和脂肪与单不饱和脂肪的比例（HR=0.76，95% CI：0.59-0.98），高血脂指数的生存率更差（HR=1.28，95% CI：1.01-1.65，P趋势=0.03）。我们观察到的诊断前饮食的健康成分与卵巢癌生存率之间的关联提高了诊断后饮食选择可能改善生存率的可能性。
The relationship between diet and survival after ovarian cancer diagnosis is unclear as a result of a limited number of studies and inconsistent findings. We examined the association between pre-diagnostic diet and overall survival in a population-based cohort (n=811) of Australian women diagnosed with invasive epithelial ovarian cancer between 2002 and 2005. Diet was measured by validated food frequency questionnaire. Deaths were ascertained up to 31 August 2014 via medical record review and Australian National Death Index linkage. We conducted Cox proportional hazards regression analysis, controlling for diagnosis age, tumour stage, grade and subtype, residual disease, smoking status, body mass index, physical activity, marital status, and energy intake. We observed improved survival with highest compared with lowest quartile of fibre intake (hazard ratio (HR)=0.69, 95% CI: 0.53–0.90, P-trend=0.002). There was a suggestion of better survival for women with highest compared with lowest intake category of green leafy vegetables (HR=0.79, 95% CI: 0.62–0.99), fish (HR=0.74, 95% CI: 0.57–0.95), poly- to mono-unsaturated fat ratio (HR=0.76, 95% CI: 0.59–0.98), and worse survival with higher glycaemic index (HR=1.28, 95% CI: 1.01–1.65, P-trend=0.03). The associations we observed between healthy components of diet pre-diagnosis and ovarian cancer survival raise the possibility that dietary choices after diagnosis may improve survival.
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影响因子：
3.8
作者：
Gifkins D;Olson SH;Paddock L;King M;Demissie K;Lu SE;Kong AN;Rodriguez-Rodriguez L;Bandera EV
通讯作者：
Bandera EV
影响因子：
4
作者：
Bellera CA;MacGrogan G;Debled M;de Lara CT;Brouste V;Mathoulin-Pélissier S
通讯作者：
Mathoulin-Pélissier S
影响因子：
4.7
作者：
Dixon, S. C.;Ibiebele, T. I.;Nagle, C. M.
通讯作者：
Nagle, C. M.
DOI：
10.1158/1055-9965.epi-13-0515
发表时间：
2014-02
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Crane TE;Khulpateea BR;Alberts DS;Basen-Engquist K;Thomson CA
通讯作者：
Thomson CA
影响因子：
--
作者：
Dolecek, Therese A.;McCarthy, Bridget J.;Davis, Faith G.
通讯作者：
Davis, Faith G.