Detection of microplastics in human colectomy specimens.
Detection of microplastics in human colectomy specimens.
复制标题
DOI：
10.1002/jgh3.12457
复制
发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
Lee YY
中科院分区：
文献类型：
--
作者：
Ibrahim YS;Tuan Anuar S;Azmi AA;Wan Mohd Khalik WMA;Lehata S;Hamzah SR;Ismail D;Ma ZF;Dzulkarnaen A;Zakaria Z;Mustaffa N;Tuan Sharif SE;Lee YY
虽然人们越来越多地认识到饮食中暴露于微塑料，但摄入的塑料是否仍留在消化道内尚不清楚。我们的目的是检查人类结肠切除标本中的微塑料，并报告颗粒的特征和聚合物组成。结肠切除样本取自马来西亚东北半岛的11名成年人(平均年龄45.7岁，6名男性)。经过样品的化学消化和随后的过滤，鉴定出了微塑料。然后使用立体和傅立叶变换红外(FTIR)显微镜检查了样品的特征(丰度、长度、形状和颜色)和三种常见聚合物类型的组成。11例标本均检出微塑料，平均为331个/个标本，平均为28.1± 15.4个/g组织。细丝或纤维占颗粒的96.1%，73.1%的细丝是透明的。在10个样品的40根随机长丝中(一根具有不确定的光谱模式)，90%是聚碳酸酯，50%是聚酰胺，40%是聚丙烯。我们的研究表明，微塑料在人类结肠中普遍存在。根据临床指征(9例结肠癌和2例正常组织学)获得11例人结肠切除标本(平均年龄45.7 ，6例男性)。所有11个标本均含有微塑料(平均每个标本331个颗粒，或每克组织28.1 ± 15.4个颗粒)。微塑料在人类结肠中无处不在。
While dietary exposure to microplastics is increasingly recognized, it is unknown if ingested plastics remain within the digestive tract. We aimed to examine human colectomy specimens for microplastics and to report the characteristics as well as polymer composition of the particles. Colectomy samples were obtained from 11 adults (mean age 45.7, six males) who were residents of Northeastern Peninsular Malaysia. Microplastics were identified following chemical digestion of specimens and subsequent filtration. The samples were then examined for characteristics (abundance, length, shape, and color) and composition of three common polymer types using stereo‐ and Fourier Transform InfraRed (FTIR) microscopes. Microplastics were detected in all 11 specimens with an average of 331 particles/individual specimen or 28.1 ± 15.4 particles/g tissue. Filaments or fibers accounted for 96.1% of particles, and 73.1% of all filaments were transparent. Out of 40 random filaments from 10 specimens (one had indeterminate spectra patterns), 90% were polycarbonate, 50% were polyamide, and 40% were polypropylene. Our study suggests that microplastics are ubiquitously present in the human colon. Eleven human colectomy samples (mean age 45.7 years old, six males) were obtained due to clinical indications (nine colon cancer and two normal histology). All 11 specimens contained microplastics (average 331 particles per individual specimen or 28.1 ± 15.4 particles per g of tissue). Microplastics are ubiquitously present in the human colon.
登录
查看更多内容
迷失但不可忽视：大量小型微塑料隐藏在南海
影响因子：
9.8
作者：
Cai, Minggang;He, Haixia;Cen, Zhengnan
通讯作者：
Cen, Zhengnan
影响因子：
4.4
作者：
Lee, Yeong Yeh;Ismail, Ahmad Wazi;Graham, David Y.
通讯作者：
Graham, David Y.
影响因子：
3.9
作者：
MCGREGOR, JR;GALLOWAY, DJ;GEORGE, WD
通讯作者：
GEORGE, WD
影响因子：
11.4
作者：
Cox, Kieran D.;Covernton, Garth A.;Dudas, Sarah E.
通讯作者：
Dudas, Sarah E.
影响因子：
9.8
作者：
Daniel, Damaris Benny;Ashraf, P. Muhamed;Thomas, Saly N.
通讯作者：
Thomas, Saly N.