Unilateral and Bilateral Laryngeal Pacing for Bilateral Vocal Fold Paralysis.
Unilateral and Bilateral Laryngeal Pacing for Bilateral Vocal Fold Paralysis.
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DOI：
10.1007/s40136-020-00313-7
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发表时间：
2020-12
影响因子：
0.6
通讯作者：
Netterville J
中科院分区：
文献类型：
--
作者：
Powell ME;Zealear DL;Li Y;Garrett CG;Von Wahlde K;Netterville J
介绍喉部起搏治疗双侧声带麻痹的最新进展。一种微创的单侧起搏系统和一种完全植入的双侧起搏系统目前正在进行临床试验。讨论了每种方法的相对优缺点。功能性电刺激复活环踝后肌的研究已经从动物模型成功地转化为人类单侧起搏和双侧起搏的临床试验。目前的研究结果表明，单侧起搏显着改善了人类的通气性，但仅略好于心脏切断术。犬双侧起搏较单侧起搏增加声门开度2倍以上，运动耐力恢复正常。单侧起搏可以被认为是一种呼吸辅助装置，可能不适合活跃的个人。对于希望进行剧烈运动的患者，双侧起搏可能是更好的选择。微创系统可能是那些喜欢较小侵入性植入且不关心美容的患者的理想选择。完全植入式起搏系统提供更大的电极冗余度和稳定性，从而使系统对电极迁移或损伤具有强大的抵抗力。
Present the state-of-the-art overview of laryngeal pacing for treatment of bilateral vocal fold paralysis. A minimally invasive unilateral pacing system and a fully implantable bilateral pacing system are currently in clinical trials. The relative advantages and disadvantages of each are discussed. Research in functional electrical stimulation for the reanimation of the posterior cricoarytenoid muscle has successfully translated from animal models to human clinical trials for unilateral pacing and bilateral pacing. Current findings suggest unilateral pacing in humans significantly improves ventilation but only marginally better than cordotomy. Bilateral pacing in canines increases glottal opening greater than 2-fold over unilateral pacing and restores exercise tolerance to normal. Unilateral pacing can be considered a breathing assist device and may not be appropriate for active individuals. Bilateral pacing may be preferable for patients who wish to engage in strenuous exercise. Minimally invasive systems may be ideal for patients who prefer less invasive implantation and are not concerned with cosmesis. Fully implantable pacing systems offer greater electrode redundancy and stability, resulting in a system that is robust against electrode migration or damage.
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影响因子：
3.4
作者：
CRUMLEY, RL;MCCABE, BF
通讯作者：
MCCABE, BF
影响因子：
1.4
作者：
ZEALEAR, DL;DEDO, HH
通讯作者：
DEDO, HH
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作者：
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通讯作者：
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作者：
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通讯作者：
Nawka, Tadeus
影响因子：
1.4
作者：
Billante, CR;Zealear, DL;Netterville, JL
通讯作者：
Netterville, JL