Efficacy of methylphenidate, psychosocial treatments and their combination in school-aged children with ADHD: a meta-analysis.
Efficacy of methylphenidate, psychosocial treatments and their combination in school-aged children with ADHD: a meta-analysis.
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哌醋甲酯、心理社会治疗及其组合对学龄多动症儿童的疗效：一项荟萃分析。
DOI：
10.1016/j.cpr.2007.10.007
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发表时间：
2008
影响因子：
12.8
通讯作者：
P. Emmelkamp
中科院分区：
文献类型：
--
作者：
S. Oord;P. Prins;J. Oosterlaan;P. Emmelkamp
本荟萃分析比较了哌醋甲酯和社会心理治疗及其联合治疗对ADHD、并发对立、行为症状、社会行为和学业功能的效应量。方法检索PubMed、PsycInfo、ISI Web of Science等数据库1985 ~ 2006年9月间发表的论文。入选标准为：诊断为ADHD；年龄6-12岁；随机对照治疗设计；用家长和教师评定量表建立疗效；使用的社会心理治疗被描述为行为或认知行为；哌甲酯治疗短效；最后，治疗在临床环境中进行。结果哌甲酯治疗和联合治疗的adhd结果均显示较大的平均加权效应量，心理社会治疗的平均加权效应量中等；在对立性和指导性行为症状中也出现了类似的模式。所有治疗的社会行为结果显示出中等的平均加权效应量，而在学术功能方面，所有治疗的平均加权效应量都很低。心理社会治疗的持续时间与效应大小之间没有相关性。结论哌甲酯和心理治疗均可有效减轻ADHD症状。然而，心理治疗的效果比其他两种治疗条件都要小。社会心理治疗对减少ADHD和教师评定的ODD症状没有额外的价值。然而，对于社会行为和家长评定的ODD，三种治疗方法同样有效。对于学业功能的改善，没有治疗是有效的。
INTRODUCTIONThis meta-analysis compares effect-sizes of methylphenidate and psychosocial treatments and their combination on ADHD, concurrent oppositional, conduct symptoms, social behaviors and academic functioning.METHODSeveral databases (PubMed, PsycInfo, ISI Web of Science) were searched for articles published between 1985 and September 2006. Inclusion criteria were: a diagnosis of ADHD; age from 6–12 years; a randomized controlled treatment design; efficacy established with parent and teacher rating scales; psychosocial treatments used were described as behavioral or cognitive-behavioral; the methylphenidate treatment was short-acting; and finally, treatment was conducted in a clinical setting.RESULTSADHD outcomes showed large mean weighted effect-sizes for both methylphenidate and combined treatments, psychosocial treatments had a moderate mean weighted effect-size; a similar pattern emerged for oppositional and conducted behavior symptoms. Social behavior outcomes showed comparable moderate mean weighted effect-sizes for all treatments, while on academic functioning, all treatments had low mean weighted effect-sizes. There was no correlation between duration of psychosocial treatment and effect-size.CONCLUSIONSBoth methylphenidate and psychosocial treatments are effective in reducing ADHD symptoms. However, psychosocial treatment yields smaller effects than both other treatment conditions. Psychosocial treatment has no additional value to methylphenidate for the reduction of ADHD and teacher rated ODD symptoms. However, for social behavior and parent rated ODD the three treatments were equally effective. For improvement of academic functioning no treatment was effective.
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抽动秽语综合征中注意力缺陷多动障碍的治疗：一项使用可乐定和地昔帕明的双盲安慰剂对照研究。
影响因子：
8
作者：
Singer,HS;Brown,J;Quaskey,S;Rosenberg,LA;Mellits,ED;Denckla,MB
通讯作者：
Denckla,MB
注意力缺陷/多动障碍（ADHD）的行为和精神刺激治疗的概括：讨论和例子。
影响因子：
4.1
作者：
Waschbusch,DA;Kipp,HL;PelhamJr,WE
通讯作者：
PelhamJr,WE
DOI：
10.1097/01.chi.0000128796.84202.eb
发表时间：
2004-07-01
影响因子：
13.3
作者：
Hechtman, L;Abikoff, H;Pollack, S
通讯作者：
Pollack, S
影响因子：
5.9
作者：
PELHAM, WE;CARLSON, C;HOZA, B
通讯作者：
HOZA, B
DOI：
10.1097/00004583-200102000-00011
发表时间：
2001-02-01
影响因子：
13.3
作者：
Swanson, JM;Kraemer, HC;Wu, M
通讯作者：
Wu, M