Cellular sources and immune functions of interleukin-9.

Cellular sources and immune functions of interleukin-9.
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DOI:
10.1038/nri2848
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发表时间:
2010-10
期刊:
Nature reviews. Immunology
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--
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--
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其他
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Interleukin-9 (IL-9) 因其在多种 T 辅助 (TH) 细胞亚群(包括 TH2 细胞、TH9 细胞、TH17 细胞和调节性 T (TReg) 细胞)中的表达而引起了新的兴趣。在这里,我们概述了细胞产生 IL-9 所需的条件,并描述了 IL-9 诱导的免疫反应的细胞靶标和性质。
Interleukin-9 (IL-9) has attracted renewed interest owing to the identification of its expression by multiple T helper (TH) cell subsets, including TH2 cells, TH9 cells, TH17 cells and regulatory T (TReg) cells. Here, we provide a broad overview of the conditions that are required for cells to produce IL-9 and describe the cellular targets and nature of the immune responses that are induced by IL-9.
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