Implementation Research for the Prevention of Mother-to-Child HIV Transmission in Sub-Saharan Africa: Existing Evidence, Current Gaps, and New Opportunities.
Implementation Research for the Prevention of Mother-to-Child HIV Transmission in Sub-Saharan Africa: Existing Evidence, Current Gaps, and New Opportunities.
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撒哈拉以南非洲的预防母亲艾滋病毒传播的实施研究：现有的证据，当前差距和新机会。
DOI：
10.1007/s11904-015-0260-1
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发表时间：
2015-06
影响因子：
4.6
通讯作者：
Chi, Benjamin H.
中科院分区：
文献类型：
--
作者：
Bhardwaj, Sanjana;Carter, Bryan;Aarons, Gregory A.;Chi, Benjamin H.
撒哈拉以南非洲在预防母婴艾滋病毒传播方面取得了巨大成就。在新的科学进步、前瞻性的卫生政策和大量捐助者投资的推动下，“实际消除”儿童艾滋病毒的宏伟目标似乎越来越可行。然而，为了实现这一承诺，必须在各种环境中迅速有效地实施循证实践。执行研究的学科可以促进这种从政策到实践的转变;然而，迄今为止，其核心原则和框架在实地的应用并不一致。我们回顾了最近的发展，在实施研究的四个“叉”的全面预防母婴传播的方法。在继续取得重大进展的同时，在研究结果的设计和传播中更加强调背景、保真度和可扩展性将大大加强目前的努力，并为未来的循证计划提供必要的基础。
Tremendous gains have been made in the prevention of mother-to-child HIV transmission (PMTCT) in sub-Saharan Africa. Ambitious goals for the “virtual elimination” of pediatric HIV appear increasingly feasible, driven by new scientific advances, forward-thinking health policy, and substantial donor investment. To fulfill this promise, however, rapid and effective implementation of evidence-based practices must be brought to scale across a diversity of settings. The discipline of implementation research can facilitate this translation from policy into practice; however, to date, its core principles and frameworks have been inconsistently applied in the field. We reviewed the recent developments in implementation research across each of the four “prongs” of a comprehensive PMTCT approach. While significant progress continues to be made, a greater emphasis on context, fidelity, and scalability – in the design and dissemination of study results – would greatly enhance current efforts and provide the necessary foundation for future evidence-based programs.
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DOI：
10.1097/qai.0b013e31825f3284
发表时间：
2012-08-15
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Chi BH;Adler MR;Bolu O;Mbori-Ngacha D;Ekouevi DK;Gieselman A;Chipato T;Luo C;Phelps BR;McClure C;Mofenson LM;Stringer JS
通讯作者：
Stringer JS
影响因子：
9.3
作者：
Ciaranello AL;Park JE;Ramirez-Avila L;Freedberg KA;Walensky RP;Leroy V
通讯作者：
Leroy V
影响因子：
3.7
作者：
Audet CM;Salato J;Blevins M;Amsalem D;Vermund SH;Gaspar F
通讯作者：
Gaspar F
DOI：
10.1097/qad.0000000000000039
发表时间：
2013-10
期刊：
AIDS (London, England)
影响因子：
--
作者：
Haddad L;Wall KM;Vwalika B;Khu NH;Brill I;Kilembe W;Stephenson R;Chomba E;Vwalika C;Tichacek A;Allen S
通讯作者：
Allen S
影响因子：
12.7
作者：
Glasgow, Russell E.;Vinson, Cynthia;Hunter, Christine
通讯作者：
Hunter, Christine