Impact of COVID-19 pandemic on the prevalence of respiratory viruses in children with lower respiratory tract infections in China.
Impact of COVID-19 pandemic on the prevalence of respiratory viruses in children with lower respiratory tract infections in China.
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DOI：
10.1186/s12985-021-01627-8
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发表时间：
2021-08-03
期刊：
影响因子：
4.8
通讯作者：
Xu J
中科院分区：
文献类型：
--
作者：
Liu P;Xu M;Cao L;Su L;Lu L;Dong N;Jia R;Zhu X;Xu J
新冠肺炎大流行期间采取的多方面非药物干预措施不仅减少了SARS-CoV-2的传播，而且对其他病毒的流行产生了影响。为了解新冠肺炎流行期间中国地区住院下呼吸道感染患儿中常见呼吸道病毒的流行情况。检测呼吸道合胞病毒(RSV)、腺病毒(ADV)、副流感病毒(PIV)1~3、流感病毒A(FluA)、流感病毒B(Flu B)、人偏肺病毒(MPV)和鼻病毒(RV)。对2020年(新冠肺炎大流行)和2019年(新冠肺炎大流行前)的数据进行了分析和比较。共纳入患者7107人，其中2019年为4600人，2020年为2507人。与2019年相比，我们观察到，尽管2020年6月学校重新开学，但RSV、ADV、FluA、Flb和MPV感染在2020年出现了前所未有的下降。然而，轮状病毒感染在2020年显著增加，特别是在学校重新开学后观察到急剧增加。此外，PIV感染在2020年9月以后呈现回升特征。与2019年相比，2020年混合感染的频率明显下降。新冠肺炎大流行期间的NPI对中国地区常见呼吸道病毒的流行有较大影响。与此同时，我们确实需要警惕随着新冠肺炎限制的放松，一些呼吸道病毒可能会卷土重来。
The multifaceted non-pharmaceutical interventions (NPIs) taken during the COVID-19 pandemic not only decrease the spreading of the SARS-CoV-2, but have impact on the prevalence of other viruses. This study aimed to explore the prevalence of common respiratory viruses among hospitalized children with lower respiratory tract infections (LRTI) in China during the COVID-19 pandemic. Respiratory specimens were obtained from children with LRTI at Children’s Hospital of Fudan University for detection of respiratory syncytial virus (RSV), adenovirus (ADV), parainfluenza virus (PIV) 1 to 3, influenza virus A (FluA), influenza virus B (FluB), human metapneumovirus (MPV) and rhinovirus (RV). The data were analyzed and compared between the year of 2020 (COVID-19 pandemic) and 2019 (before COVID-19 pandemic). A total of 7107 patients were enrolled, including 4600 patients in 2019 and 2507 patients in 2020. Compared with 2019, we observed an unprecedented reduction of RSV, ADV, FluA, FluB, and MPV infections in 2020, despite of reopening of schools in June, 2020. However, the RV infection was significantly increased in 2020 and a sharp increase was observed especially after reopening of schools. Besides, the PIV infection showed resurgent characteristic after September of 2020. The mixed infections were significantly less frequent in 2020 compared with the year of 2019. The NPIs during the COVID-19 pandemic have great impact on the prevalence of common respiratory viruses in China. Meanwhile, we do need to be cautious of a possible resurgence of some respiratory viruses as the COVID-19 restrictions are relaxed.
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影响因子：
16.6
作者：
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影响因子：
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通讯作者：
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通讯作者：
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