Accuracy of self-reported tobacco use in newly diagnosed cancer patients.
Accuracy of self-reported tobacco use in newly diagnosed cancer patients.
复制标题
DOI：
10.1007/s10552-013-0202-4
复制
发表时间：
2013-06
期刊：
影响因子：
--
通讯作者：
Warren GW
中科院分区：
文献类型：
--
作者：
Morales NA;Romano MA;Michael Cummings K;Marshall JR;Hyland AJ;Hutson A;Warren GW
准确识别烟草使用情况对于在癌症患者中实施基于证据的戒烟治疗至关重要。本研究的目的是评估新诊断癌症患者自我报告烟草使用的准确性。研究人员收集了233名新诊断的癌症患者（77名肺癌患者、77名乳腺癌患者和79名前列腺癌患者）的烟草使用问卷和血液样本。使用市售的酶联免疫吸附法分析血液中可替宁的水平。可替宁测量值超过10 ng/mL的患者被归类为当前吸烟者。基于可替宁水平的吸烟状况与当前吸烟者、最近戒烟者（戒烟1年或不到1年）、非最近戒烟者（戒烟10年以上）和从不吸烟者的自我报告进行对比。多变量分析用于确定自我报告和生化证实吸烟之间不一致的潜在预测因素。可替宁证实了当前吸烟者和从不吸烟者自我报告的100%准确性。26例（15.0%）患者报告既往吸烟史，可替宁与吸烟状况不一致。自我报告吸烟不一致性最近戒烟者（35.4%）比非最近戒烟者（2.8%）高12倍。结合疾病地点、包装年份历史和就业状况预测了82.4%的近期戒烟者对烟草使用的不实陈述。自我报告的烟草使用可能不能准确评估新诊断癌症患者的吸烟状况。声称最近在癌症诊断前一年内戒烟的患者和肺癌患者可能更倾向于歪曲烟草使用情况，并可能从生化证实中受益。
Accurate identification of tobacco use is critical to implement evidence-based cessation treatments in cancer patients. The purpose of this study is to evaluate the accuracy of self-reported tobacco use in newly diagnosed cancer patients. Tobacco use questionnaires and blood samples were collected from 233 newly diagnosed cancer patients (77 lung, 77 breast, and 79 prostate cancer). Blood was analyzed for cotinine levels using a commercially available enzyme-linked immunosorbent assay. Patients with cotinine measurements exceeding 10 ng/mL were categorized as current smokers. Smoking status based upon cotinine levels was contrasted with self-report in current smokers, recent quitters (1 or less year since quit), non-recent quitters (>1 year since quit), and never smokers. Multivariate analyses were used to identify potential predictors of discordance between self-reported and biochemically confirmed smoking. Cotinine confirmed 100 % accuracy in self-reporting of current and never smokers. Discordance in cotinine and smoking status was observed in 26 patients (15.0 %) reporting former tobacco use. Discordance in self-reported smoking was 12 times higher in recent (35.4 %) as compared with non-recent quitters (2.8 %). Combining disease site, pack-year history, and employment status predicted misrepresentation of tobacco use in 82.4 % of recent quitters. Self-reported tobacco use may not accurately assess smoking status in newly diagnosed cancer patients. Patients who claim to have recently stopped smoking within the year prior to a cancer diagnosis and lung cancer patients may have a higher propensity to misrepresent tobacco use and may benefit from biochemical confirmation.
登录
查看更多内容
DOI：
10.1007/s11764-010-0147-5
发表时间：
2011-06
期刊：
Journal of cancer survivorship : research and practice
影响因子：
--
作者：
Jang S;Prizment A;Haddad T;Robien K;Lazovich D
通讯作者：
Lazovich D
影响因子：
120.7
作者：
Kenfield, Stacey A.;Stampfer, Meir J.;Chan, June M.;Giovannucci, Edward
通讯作者：
Giovannucci, Edward
影响因子：
6.6
作者：
Boorjian, Stephen;Cowan, Janet E.;Kane, Christopher J.
通讯作者：
Kane, Christopher J.
影响因子：
1.5
作者：
Goodwin, SJ;McCarthy, CM;Mehrara, BJ
通讯作者：
Mehrara, BJ
影响因子：
3.7
作者：
GOLDBERG, JD
通讯作者：
GOLDBERG, JD