Validity of Body Mass Index as a Measure of Adiposity in Infancy.
Validity of Body Mass Index as a Measure of Adiposity in Infancy.
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DOI：
10.1016/j.jpeds.2018.01.028
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发表时间：
2018-05
期刊：
影响因子：
--
通讯作者：
Belfort MB
中科院分区：
文献类型：
--
作者：
Bell KA;Wagner CL;Perng W;Feldman HA;Shypailo RJ;Belfort MB
评估婴儿期3个时间点（1、4和7个月）BMI和年龄和性别标准化BMI z评分（BMIZ）作为肥胖替代指标[体脂百分比（BF%）、脂肪量和脂肪量指数（FMI，kg/m2）]的有效性，并评估BMIZ变化代表肥胖变化的程度。我们对447名足月婴儿进行了二次分析，这些婴儿在先前的哺乳期母亲补充维生素D的试验中。研究人员测量了婴儿的人体测量学，并在1个月、4个月和7个月时用双能x线吸收法评估了身体成分。我们计算了每个时间点BMI、BMIZ和肥胖之间的斯皮尔曼相关性（rs），以及不同时间点BMIZ变化和肥胖变化之间的相关性。婴儿（N=447）52%为男性; 37%为白色，31%为黑人，30%为西班牙裔。BMIZ与BF%中度相关（1、4和7个月时rs分别为0.43、0.55和0.48）。BMIZ与脂肪量和FMI的相关性更强，特别是在4个月和7个月时（脂肪量rs=0.72-0.76; FMI rs=0.75-0.79）。BMIZ的变化与1-4个月的肥胖变化中度相关（BF%变化rs=0.44;脂肪量变化rs=0.53），但4-7个月仅弱相关（BF%变化rs=0.21;脂肪量变化rs=0.27）。BMIZ与婴儿期肥胖中度相关。BMIZ的变化是婴儿后期肥胖变化的不良指标。BMI和BMIZ作为肥胖的替代物是有限的，特别是婴儿期的肥胖变化。
To assess the validity of BMI and age- and sex-standardized BMI z-score (BMIZ) as surrogates for adiposity [body fat percentage (BF%), fat mass, and fat mass index (FMI, kg/m2)] at three time points in infancy (1, 4, and 7 months), and to assess the extent to which change in BMIZ represents change in adiposity. We performed a secondary analysis of 447 full-term infants in a previous trial of maternal vitamin D supplementation during lactation. Study staff measured infant anthropometrics and assessed body composition with dual-energy x-ray absorptiometry at 1, 4, and 7 months. We calculated Spearman correlations (rs) among BMI, BMIZ, and adiposity at each time point, and between change in BMIZ and change in adiposity between time points. Infants (N=447) were 52% male; 37% white, 31% black, 30% Hispanic. BMIZ was moderately correlated with BF% (rs=0.43, 0.55, 0.48 at 1, 4, and 7 months respectively). BMIZ correlated more strongly with fat mass and FMI, particularly at 4 and 7 months (fat mass rs=0.72–0.76; FMI rs=0.75–0.79). Changes in BMIZ were moderately correlated with adiposity changes from 1–4 months (rs=0.44 with BF% change; rs=0.53 with fat mass change), but only weakly correlated from 4–7 months (rs=0.21 with BF% change; rs=0.27 with fat mass change). BMIZ is moderately correlated with adiposity in infancy. Changes in BMIZ are a poor indicator of adiposity changes in later infancy. BMI and BMIZ are limited as surrogates for adiposity and especially adiposity changes in infancy.
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DOI：
10.1056/nejmoa1309753
发表时间：
2014-01-30
期刊：
The New England journal of medicine
影响因子：
--
作者：
Cunningham SA;Kramer MR;Narayan KM
通讯作者：
Narayan KM
影响因子：
7.1
作者：
Perng, Wei;Ringham, Brandy M.;Dabelea, Dana
通讯作者：
Dabelea, Dana
影响因子：
7.1
作者：
DEWEY, KG;HEINIG, MJ;LONNERDAL, B
通讯作者：
LONNERDAL, B
影响因子：
8
作者：
Hollis, Bruce W.;Wagner, Carol L.;Hulsey, Thomas C.
通讯作者：
Hulsey, Thomas C.
DOI：
10.1007/978-1-4020-9173-5_19
发表时间：
2009-01-01
期刊：
EARLY NUTRITION PROGRAMMING AND HEALTH OUTCOMES IN LATER LIFE: OBESITY AND BEYOND
影响因子：
--
作者：
Chomtho, Sirinuch;Wells, Jonathan C. K.;Fewtrell, Mary S.
通讯作者：
Fewtrell, Mary S.