Polymorphism and evolutionary profile of mitochondrial DNA control region inferred from the sequences of Pakistani goats
Polymorphism and evolutionary profile of mitochondrial DNA control region inferred from the sequences of Pakistani goats
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巴基斯坦山羊线粒体DNA控制区的多态性和进化谱
DOI：
10.1111/j.1740-0929.2004.00190.x
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发表时间：
2004
影响因子：
2
通讯作者：
H. Mannen
中科院分区：
文献类型：
--
作者：
S. Sultana;H. Mannen
对30只巴基斯坦家山羊线粒体DNA控制区全序列进行了测定，以研究其遗传多样性和遗传组织。共观察到22种新的单倍型，均属于线粒体谱系A。系统发育分析显示，两个不同的集群在线粒体谱系A，A1和A2。一个17 bp的缺失和一个76 bp的插入被检测到的L-结构域，观察10和1只动物，分别在232巴基斯坦家山羊。这些显著的缺失/插入事件将有助于研究高度分化的线粒体谱系A内的mtDNA多样性。在控制区特征分析中，山羊mtDNA与其他偶蹄动物一样富含A/T。与其他物种一样，确定了四个保守区，即L结构域中的A区、C结构域、R结构域中的B区和CSB 1区。
Complete mitochondrial DNA (mtDNA) control region of 30 Pakistani domestic goats was sequenced to investigate the genetic diversity and organization. Twenty-two new haplotypes were observed and all were classified into mt-lineage A. Phylogenetic analysis revealed two distinct clusters in mt-lineage A, A1 and A2. A 17 bp deletion and a 76 bp insertion were detected in the L-domain and observed 10 and one animals, respectively, in 232 Pakistani domestic goats. These remarkable deletion/insertion events would be useful to investigate mtDNA diversity within the highly divergent mt-lineage A. In analysis of the control region feature, the caprine mtDNA was A/T rich as observed for other artiodactyls. Four conserved regions, Block A in the L domain, the C-domain, Block B and CSB1 in the R domain, were defined as well as in the other species.
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DOI：
--
发表时间：
1993
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Ghivizzani,SC;Madsen,CS;Hauswirth,WW
通讯作者：
Hauswirth,WW
影响因子：
3.3
作者：
R. Cann;W. Brown;A. Wilson
通讯作者：
R. Cann;W. Brown;A. Wilson
DOI：
10.1073/pnas.78.10.6116
发表时间：
1981-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
DODA, JN;WRIGHT, CT;CLAYTON, DA
通讯作者：
CLAYTON, DA
影响因子：
12
作者：
Kitjacharoenchai, Patchara;Min, Byung-Cheol;Lee, Seokcheon
通讯作者：
Lee, Seokcheon