Improving Automatic Renal Segmentation in Clinically Normal and Abnormal Paediatric DCE-MRI via Contrast Maximisation and Convolutional Networks for Computing Markers of Kidney Function.
Improving Automatic Renal Segmentation in Clinically Normal and Abnormal Paediatric DCE-MRI via Contrast Maximisation and Convolutional Networks for Computing Markers of Kidney Function.
复制标题
通过对比度最大化和卷积网络计算肾功能标记物,改进临床正常和异常儿科 DCE-MRI 的自动肾脏分割。
DOI:
10.3390/s21237942
复制
发表时间:
2021-11-28
期刊:
影响因子:
--
通讯作者:
Kurugol S
中科院分区:
文献类型:
--
作者:
Asaturyan H;Villarini B;Sarao K;Chow JS;Afacan O;Kurugol S
There is a growing demand for fast, accurate computation of clinical markers to improve renal function and anatomy assessment with a single study. However, conventional techniques have limitations leading to overestimations of kidney function or failure to provide sufficient spatial resolution to target the disease location. In contrast, the computer-aided analysis of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) could generate significant markers, including the glomerular filtration rate (GFR) and time–intensity curves of the cortex and medulla for determining obstruction in the urinary tract. This paper presents a dual-stage fully modular framework for automatic renal compartment segmentation in 4D DCE-MRI volumes. (1) Memory-efficient 3D deep learning is integrated to localise each kidney by harnessing residual convolutional neural networks for improved convergence; segmentation is performed by efficiently learning spatial–temporal information coupled with boundary-preserving fully convolutional dense nets. (2) Renal contextual information is enhanced via non-linear transformation to segment the cortex and medulla. The proposed framework is evaluated on a paediatric dataset containing 60 4D DCE-MRI volumes exhibiting varying conditions affecting kidney function. Our technique outperforms a state-of-the-art approach based on a GrabCut and support vector machine classifier in mean dice similarity (DSC) by 3.8% and demonstrates higher statistical stability with lower standard deviation by 12.4% and 15.7% for cortex and medulla segmentation, respectively.
登录
查看更多内容
DOI:
10.1016/b978-0-12-815876-0.00078-4
发表时间:
2020-01-01
期刊:
CHRONIC RENAL DISEASE, 2ND EDITION
影响因子:
--
作者:
Cohen, Scott D.;Davison, Sara N.;Kimmel, Paul L.
通讯作者:
Kimmel, Paul L.
影响因子:
3.3
作者:
Feng, Li;Grimm, Robert;Block, Kai Tobias;Chandarana, Hersh;Kim, Sungheon;Xu, Jian;Axel, Leon;Sodickson, Daniel K.;Otazo, Ricardo
通讯作者:
Otazo, Ricardo
DOI:
10.1109/isbi.2018.8363865
发表时间:
2018-04
期刊:
Proceedings. IEEE International Symposium on Biomedical Imaging
影响因子:
--
作者:
Haghighi M;Warfield SK;Kurugol S
通讯作者:
Kurugol S
影响因子:
3.2
作者:
Abdi, Herve;Williams, Lynne J.
通讯作者:
Williams, Lynne J.
影响因子:
2.5
作者:
Kong, Hanjing;Chen, Bin;Zhang, Jue
通讯作者:
Zhang, Jue