Impact of Social Distancing Due to Coronavirus Disease 2019 on the Changes in Glycosylated Hemoglobin Level in People with Type 2 Diabetes Mellitus.
Impact of Social Distancing Due to Coronavirus Disease 2019 on the Changes in Glycosylated Hemoglobin Level in People with Type 2 Diabetes Mellitus.
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DOI：
10.4093/dmj.2020.0226
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发表时间：
2021-01
影响因子：
5.9
通讯作者：
Park KG
中科院分区：
文献类型：
--
作者：
Park SD;Kim SW;Moon JS;Lee YY;Cho NH;Lee JH;Jeon JH;Choi YK;Kim MK;Park KG
本研究调查了2019冠状病毒病（COVID-19）导致的社交距离对2型糖尿病（T2 DM）患者血糖控制的影响。我们回顾性分析了因COVID-19而进行社交距离的T2 DM患者的糖化血红蛋白水平（Δ HbA 1c）变化。我们比较了在一年中同一时间入组的COVID-19和非COVID-19队列之间的Δ HbA 1c。COVID-19队列的Δ HbA 1c显著高于两个非COVID-19队列。根据年龄和基线HbA 1c水平进行的亚组分析显示，社交距离显著增加了<50岁参与者的平均HbA 1c水平。COVID-19队列中<50岁且HbA 1c <7.0%的参与者的Δ HbA 1c变化大于其他亚组。在调整后的模型中，COVID-19队列的调整后Δ HbA 1c水平仍显著高于其他两个队列。社交距离对T2 DM患者的血糖控制有负面影响，尤其是那些年轻且血糖控制良好的患者。
This study investigated the impact of social distancing due to coronavirus disease 2019 (COVID-19) on glycemic control in people with type 2 diabetes mellitus (T2DM). We retrospectively analyzed the change in glycosylated hemoglobin level (ΔHbA1c) in people with T2DM who undertook social distancing because of COVID-19. We compared the ΔHbA1c between COVID-19 and non-COVID-19 cohorts that were enrolled at the same time of year. The ΔHbA1c of the COVID-19 cohort was significantly higher than that of two non-COVID-19 cohorts. Subgroup analysis according to age and baseline HbA1c level showed that social distancing significantly increased the mean HbA1c level of participants of <50 years. The ΔHbA1c of participants of <50 years and with HbA1c <7.0% in the COVID-19 cohort showed larger changes than other subgroups. In adjusted model, adjusted ΔHbA1c levels in the COVID-19 cohort remained significantly higher than those in the two other cohorts. Social distancing negatively impacts blood glucose control in people with T2DM, especially those who are younger and have good blood glucose control.
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