Association of Epstein-Barr Virus with Hodgkin’s Disease
Association of Epstein-Barr Virus with Hodgkin’s Disease
复制标题
EB 病毒与霍奇金病的关联
DOI:
10.1007/978-1-4899-1100-1_20
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发表时间:
1995
期刊:
影响因子:
--
通讯作者:
A. Gloghini
中科院分区:
文献类型:
--
作者:
M. Boiocchi;R. Dolcetti;V. Re;A. Carbone;A. Gloghini
The nature of Hodgkin’s disease (HD) and the origin of its characteristic cells, the Reed-Sternberg (RS) cells, are still obscure in spite of the abundant literature on this disorder. In recent years, the concept that HD is a malignant lymphoma has become widely accepted among pathologists, clinicians, and medical researchers working on this disease. However, the evidence accumulated so far with regard to the standard parameters defining neoplastic proliferation, such as clonality, chromosomal abnormality, and transplantability, is still controversial. A further enigma concerning HD as a neoplastic lymphoproliferative disease is the extremely low percentage of putative neoplastic cells (RS cells and their variants) occurring in the polymorphic histopathological setting that characterizes the disease. In contrast, well-recognized neoplastic lymphoproliferative diseases, the so-called non-Hodgkin’s lymphomas (NHLs), usually show monomorphic histological patterns and are constituted predominantly of monoclonal or, more rarely, oligoclonal cell populations.
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影响因子:
8
作者:
L. Hu;Fu Chen;Xi Zheng;I. Ernberg;S. Cao;B. Christensson;G. Klein;G. Winberg
通讯作者:
L. Hu;Fu Chen;Xi Zheng;I. Ernberg;S. Cao;B. Christensson;G. Klein;G. Winberg
DOI:
--
发表时间:
1985
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
DeKruyff,RH;Brown,PH;Thorbecke,GJ;Ponzio,NM
通讯作者:
Ponzio,NM
影响因子:
3.8
作者:
HU, LF;ZABAROVSKY, ER;WINBERG, G
通讯作者:
WINBERG, G
DOI:
--
发表时间:
1989
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Katz,JD;Lebow,LT;Bonavida,B
通讯作者:
Bonavida,B
DOI:
--
发表时间:
1988
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Lasky,JL;Ponzio,NM;Thorbecke,GJ
通讯作者:
Thorbecke,GJ