Chlamydia trachomatis infection during pregnancy associated with preterm delivery: a population-based prospective cohort study.
Chlamydia trachomatis infection during pregnancy associated with preterm delivery: a population-based prospective cohort study.
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DOI：
10.1007/s10654-011-9586-1
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发表时间：
2011-06
影响因子：
13.6
通讯作者：
Verbrugh, Henri A.
中科院分区：
文献类型：
--
作者：
Rours, G. Ingrid J. G.;Duijts, Liesbeth;Moll, Henriette A.;Arends, Lidia R.;de Groot, Ronald;Jaddoe, Vincent W.;Hofman, Albert;Steegers, Eric A. P.;Mackenbach, Johan P.;Ott, Alewijn;Willemse, Hendrina F. M.;van der Zwaan, Elizabeth A. E.;Verkooijen, Roel P.;Verbrugh, Henri A.
沙眼衣原体感染是最常见的细菌性传播感染，并可能影响妊娠结局。本研究旨在评估妊娠期衣原体感染对早产和出生体重的影响。在2003年2月至2005年1月期间参加助产实践或产前诊所的孕妇有资格参加这项研究。从4,055名妇女的自我问卷调查和尿液样本，通过PCR检测，分析了C。沙眼感染从助产士和医院登记处获得妊娠结局。对3 913名新生儿的出生年龄和出生体重进行了分析。梭沙眼患病率为3.9%，但因年龄和社会经济背景而异。校正潜在混杂因素后，衣原体感染与妊娠32周（OR 4.35 [95% CI 1.3，15.2]）和35周（OR 2.66 [95% CI 1.1，6.5]）前早产相关，但与低出生体重无关。在妊娠32周和35周前的所有分娩中，14.9% [95% CI 4.5，39.5]和7.4% [95% CI 2.5，20.1]归因于C。沙眼感染沙眼衣原体感染对早期早产有显著影响，应被视为一个公共卫生问题，特别是在年轻妇女和其他感染沙眼衣原体风险增加的妇女中。沙眼感染
Chlamydia trachomatis infection is the most prevalent bacterial sexually transmitted infection and may influence pregnancy outcome. This study was conducted to assess the effect of chlamydial infection during pregnancy on premature delivery and birthweight. Pregnant women attending a participating midwifery practice or antenatal clinic between February 2003 and January 2005 were eligible for the study. From 4,055 women self-administered questionnaires and urine samples, tested by PCR, were analysed for C. trachomatis infection. Pregnancy outcomes were obtained from midwives and hospital registries. Gestational ages and birthweights were analysed for 3,913 newborns. The C. trachomatis prevalence was 3.9%, but varied by age and socio-economic background. Chlamydial infection was, after adjustment for potential confounders, associated with preterm delivery before 32 weeks (OR 4.35 [95% CI 1.3, 15.2]) and 35 weeks gestation (OR 2.66 [95% CI 1.1, 6.5]), but not with low birthweight. Of all deliveries before 32 weeks and 35 weeks gestation 14.9% [95% CI 4.5, 39.5] and 7.4% [95% CI 2.5, 20.1] was attributable to C. trachomatis infection. Chlamydia trachomatis infection contributes significantly to early premature delivery and should be considered a public health problem, especially in young women and others at increased risk of C. trachomatis infection.
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DOI：
10.1016/j.ejogrb.2005.04.004
发表时间：
2005-09-01
期刊：
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY
影响因子：
--
作者：
Bernloehr, A;Smith, P;Vydelingum, V
通讯作者：
Vydelingum, V
影响因子：
3.6
作者：
Groves, J.;Newton, D. C.;Fairley, C. K.
通讯作者：
Fairley, C. K.
DOI：
10.1016/s0020-7292(98)00075-7
发表时间：
1998-07-01
影响因子：
3.8
作者：
Kovács, L;Nagy, E;Nyári, T
通讯作者：
Nyári, T
DOI：
10.1016/s0002-9378(88)80093-0
发表时间：
1988-08-01
影响因子：
9.8
作者：
ALGER, LS;LOVCHIK, JC;CRENSHAW, MC
通讯作者：
CRENSHAW, MC
DOI：
10.1111/j.1651-2227.1991.tb11945.x
发表时间：
1991-08-01
期刊：
ACTA PAEDIATRICA SCANDINAVICA
影响因子：
--
作者：
NIKLASSON, A;ERICSON, A;KARLBERG, P
通讯作者：
KARLBERG, P