Significance of hydrogen bonding at the S(1)' subsite of calpain I.
Significance of hydrogen bonding at the S(1)' subsite of calpain I.
复制标题
钙蛋白酶 I S(1) 亚位点氢键的意义。
DOI:
10.1016/s0960-894x(01)00301-8
复制
发表时间:
2001
影响因子:
2.7
通讯作者:
Miller,DD
中科院分区:
文献类型:
--
作者:
Donkor,IO;Zheng,X;Han,J;Lacy,C;Miller,DD
α-Ketohydroxamates were synthesized as bioisosteres of α-ketoamides. The α-ketohydroxamates were generally more potent than the corresponding α-ketoamides. The potency of the compounds suggests that hydrogen bonding and steric bulk of substituents on the nitrogen atom of the ketoamide moiety influence calpain inhibition.
影响因子:
2.7
作者:
Chatterjee, S;Dunn, D;Mallamo, JP
通讯作者:
Mallamo, JP
影响因子:
6.6
作者:
G. Wells;R. Bihovsky
通讯作者:
R. Bihovsky