Incidence Trends of Kaposi Sarcoma Among Young Non-Hispanic Black Men by US Regions, 2001-2018.

Incidence Trends of Kaposi Sarcoma Among Young Non-Hispanic Black Men by US Regions, 2001-2018.
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DOI:
10.1093/jncics/pkac078
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发表时间:
2022-11-01
影响因子:
4.4
通讯作者:
--
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其他
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尽管在美国,艾滋病毒感染者中卡波西肉瘤(KS)的总体发病率呈下降趋势,但先前的研究表明,美国特定人群亚组的卡波西肉瘤发病率可能高于其他人群。我们利用2001 - 2018年国家癌症登记计划以及监测、流行病学和最终结果计划数据库,按种族、族裔和地理区域评估了20 - 34岁年轻男性的卡波西肉瘤发病趋势。统计学显著性采用双侧检验。美国非西班牙裔黑人男性的卡波西肉瘤发病率每年上升1.5%,而非西班牙裔白人男性的发病率每年显著下降3.5%。研究观察到,美国南部年轻非西班牙裔黑人男性的发病率每年显著上升3.3%,而居住在南部以外地区的该群体发病率则无变化。因此,有必要针对美国南部年轻非西班牙裔黑人男性开展有针对性的艾滋病毒预防和治疗工作,并进一步研究这一弱势群体中卡波西肉瘤发病率上升及其负担加重的问题。
Despite the overall national decline in Kaposi sarcoma (KS) incidence in the United States among persons living with HIV, previous studies suggest there might be specific subgroups of the US population that are associated with higher KS incidence rates than others. Using the 2001-2018 National Program of Cancer Registries and Surveillance, Epidemiology, and End Results Program database, we assessed KS incidence trends among young men aged 20-34 years by race and ethnicity and geographic region. Statistical significance is 2-sided. The KS incidence rate increased nationally by 1.5% per year in non-Hispanic Black men, whereas the rate decreased statistically significantly by 3.5% per year in non-Hispanic White men. A statistically significant 3.3% per year increase among young non-Hispanic Black men in the South and no change among those living in non-South regions were observed. Targeted HIV prevention and treatment in young non-Hispanic Black men in the South and further research addressing the increased KS incidence and burden in this vulnerable population are needed.
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