Realistic boundary conditions in SimVascular through inlet catheter modeling.
Realistic boundary conditions in SimVascular through inlet catheter modeling.
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DOI：
10.1186/s13104-021-05631-7
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发表时间：
2021-05-31
影响因子：
1.8
通讯作者：
Roncali E
中科院分区：
文献类型：
--
作者：
Taebi A;Berk S;Roncali E
本研究旨在开发一种管道，该管道能够将导管效应纳入使用开源软件SimVascular进行的心血管系统和其他人体血管流动的计算流体动力学（CFD）模拟中。该工具对于介入放射学程序的CFD模拟特别有用，例如肿瘤栓塞，其中对治疗剂分布的估计感兴趣。开发了一个管道，用于生成可用于SimVascular CFD模拟的边界条件文件。修改边界条件文件，使其模拟导管存在对入口下游流场的影响。使用该管道，可以定义导管流量、速度分布、半径、壁厚和与血管中心的偏差。由于我们的方法依赖于对施加在入口上的边界条件的操纵，因此它对网格密度敏感。网格越细（尤其是导管壁周围），速度估计就越准确。在这项研究中，我们还利用该管道定性研究导管存在对肝癌患者截断的肝右动脉树中的流场的影响。在线版本包含补充材料，可通过10.1186/s13104-021-05631-7获得。
This study aims at developing a pipeline that provides the capability to include the catheter effect in the computational fluid dynamics (CFD) simulations of the cardiovascular system and other human vascular flows carried out with the open-source software SimVascular. This tool is particularly useful for CFD simulation of interventional radiology procedures such as tumor embolization where estimation of a therapeutic agent distribution is of interest. A pipeline is developed that generates boundary condition files which can be used in SimVascular CFD simulations. The boundary condition files are modified such that they simulate the effect of catheter presence on the flow field downstream of the inlet. Using this pipeline, the catheter flow, velocity profile, radius, wall thickness, and deviation from the vessel center can be defined. Since our method relies on the manipulation of the boundary condition that is imposed on the inlet, it is sensitive to the mesh density. The finer the mesh is (especially around the catheter wall), the more accurate the velocity estimations are. In this study, we also utilized this pipeline to qualitatively investigate the effect of catheter presence on the flow field in a truncated right hepatic arterial tree of a liver cancer patient. The online version contains supplementary material available at 10.1186/s13104-021-05631-7.
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