Mood disorders, childhood maltreatment, and medical morbidity in US adults: An observational study.
Mood disorders, childhood maltreatment, and medical morbidity in US adults: An observational study.
复制标题
美国成年人的情绪障碍、儿童虐待和医疗发病率：一项观察性研究。
DOI：
10.1016/j.jpsychores.2020.110207
复制
发表时间：
2020-07-28
影响因子：
4.7
通讯作者：
Gallo JJ
中科院分区：
文献类型：
--
作者：
Stapp EK;Williams SC;Kalb LG;Holingue CB;Van Eck K;Ballard ED;Merikangas KR;Gallo JJ
情绪障碍、儿童虐待和医疗发病率与巨大的公共卫生负担和个人痛苦有关。情绪障碍对医疗发病率的影响，考虑到儿童虐待，尚未在美国社区居住成年人的大型代表性样本中进行前瞻性研究。本研究测试了情绪障碍和儿童虐待对医疗发病率的影响，以及亚型的变化。参与者是参加全国酒精及相关疾病流行病学调查的非机构美国成年人（N= 43093波1，N= 34653波2）。心境障碍包括DSM-IV中抑郁、心境恶劣、躁狂或轻躁狂的终生发作。儿童虐待被定义为18岁之前的性、身体或情感虐待，或身体或情感忽视。使用调查加权零膨胀泊松回归来研究对医疗发病率的影响，这是11种自我报告的医疗状况的汇总评分。结果根据年龄、性别、民族/种族、收入、物质使用障碍、吸烟和肥胖进行了调整。情绪障碍和儿童虐待与研究开始时和三年后的医疗发病率相关，其程度与肥胖和吸烟相似。躁狂/轻躁狂（发病率比[IRR] 1.06, 95% CI 1.01-1.10）、儿童性虐待（发病率比[IRR] 1.08, 95% CI 1.04-1.11）和情绪虐待（发病率比[IRR] 1.05, 95% CI 1.01-1.10）与较高的医疗发病率相关。儿童虐待是常见的，其对医疗发病率的长期负面影响强调了创伤知情护理的重要性，并考虑到早期生活暴露。在医疗实践中应考虑躁狂/轻躁狂病史，在精神卫生保健中必须强调身体健康。
Mood disorders, child maltreatment, and medical morbidity are associated with enormous public health burden and individual suffering. The effect of mood disorders on medical morbidity, accounting for child maltreatment, has not been studied prospectively in a large, representative sample of community-dwelling US adults. This study tested the effects of mood disorders and child maltreatment on medical morbidity, and variation by subtypes. Participants were noninstitutionalized US adults in the National Epidemiologic Survey on Alcohol and Related Conditions (N=43,093 wave 1, N=34,653 wave 2). Mood disorders included lifetime DSM-IV episodes of depression, dysthymia, mania, or hypomania. Child maltreatment was defined as sexual, physical, or emotional abuse, or physical or emotional neglect before age 18. Survey-weighted zero-inflated poisson regression was used to study effects on medical morbidity, a summary score of 11 self-reported medical conditions. Results were adjusted for age, sex, ethnicity/race, income, substance use disorders, smoking, and obesity. Mood disorders and child maltreatment additively associated with medical morbidity at study entry and three years later, with similar magnitude as obesity and smoking. Mania/hypomania (incidence rate ratio [IRR] 1.06, 95% CI 1.01–1.10) and child sexual (IRR 1.08, 95% CI 1.04–1.11) and emotional (IRR 1.05, 95% CI 1.01–1.10) abuse were associated with higher medical morbidity longitudinally. Child maltreatment is common, and its long-range negative effect on medical morbidity underscores the importance of trauma-informed care, and consideration of early life exposures. History of mania/hypomania should be considered in medical practice, and physical health must be emphasized in mental health care.
登录
查看更多内容
影响因子：
4.8
作者：
Afifi, Tracie O.;Mather, Amber;Sareen, Jitender
通讯作者：
Sareen, Jitender
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
8
作者：
Dube, SR;Felitti, VJ;Anda, RF
通讯作者：
Anda, RF
影响因子：
17.7
作者：
Edwards, VJ;Holden, GW;Anda, RF
通讯作者：
Anda, RF
影响因子：
7.3
作者：
Chou, S. Patricia;Huang, Boji;Grant, Bridget F.
通讯作者：
Grant, Bridget F.