Can Millet Consumption Help Manage Hyperlipidemia and Obesity?: A Systematic Review and Meta-Analysis.
Can Millet Consumption Help Manage Hyperlipidemia and Obesity?: A Systematic Review and Meta-Analysis.
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DOI：
10.3389/fnut.2021.700778
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发表时间：
2021
影响因子：
5
通讯作者：
Bhandari RK
中科院分区：
文献类型：
--
作者：
Anitha S;Botha R;Kane-Potaka J;Givens DI;Rajendran A;Tsusaka TW;Bhandari RK
小米（广义上也包括高粱）的许多健康益处一直被提倡，包括它们在管理和预防糖尿病方面的作用;然而，小米对高脂血症（高血脂水平）的影响一直被低估。进行了一项系统综述和荟萃分析，以整理小米消费对血脂谱影响的现有证据，即总胆固醇（TC）、三酰甘油、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）和极低密度脂蛋白胆固醇（VLDL-C）。来自19项研究的结果表明，食用小米21天至4个月的短时间内，TC、三酰甘油、LDL-C和VLDL-C水平分别降低8.0%、9.5%、10%和9.0%（p<0.01）。四项研究表明，食用小米使TC和三酰甘油水平达到正常水平（分别<200和<150 mg/dl）。此外，在食用基于小米的膳食后，HDL-C增加6.0%，收缩压和舒张压降低5.0%，体重指数（BMI）降低7.0%。这一证据使我们得出结论，食用小米可降低高脂血症，从而降低高血压，并提高HDL-C（好胆固醇）水平，这可能有利于管理未来发生高血压和动脉粥样硬化性心血管疾病的相关风险。系统综述注册：本系统评价的方案已在名为“research registry”的在线注册平台注册，唯一识别号为“reviewregistry 1123”。
Many health benefits of millets (defined broadly to also include sorghum) have been advocated, including their roles in managing and preventing diabetes; however, the effects of millets on hyperlipidemia (high lipid levels) have been underrecognized. A systematic review and meta-analysis were conducted to collate available evidence of the impacts of millets consumption on lipid profile, namely total cholesterol (TC), triacylglycerol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and very-low–density lipoprotein cholesterol (VLDL-C). The results from 19 studies showed that the consumption of millets for periods as short as 21 days to 4 months reduced levels of TC, triacylglycerol, LDL-C, and VLDL-C (p<0.01) by 8.0, 9.5, 10 and 9.0%, respectively. Four studies demonstrated that millets consumption brought TC and triacylglycerol levels to the normal levels (<200 and <150 mg/dl, respectively). Furthermore, upon consumption of millet-based meals, there was a 6.0% increase in the HDL-C 4.0 and 5.0% reduction in systolic and diastolic blood pressure, and 7.0% reduction in body mass index (BMI). This evidence, leads us to conclude that consumption of millets reduces hyperlipidemia and hence hypertension, and raises the levels of HDL-C (good cholesterol), which can be beneficial for managing the associated risk of developing hypertension and atherosclerotic cardiovascular diseases in future. Systematic Review Registration: The protocol of this systematic review has been registered in the online registration platform called “research registry” with the unique identification number “reviewregistry1123.”
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影响因子：
5
作者：
Anitha S;Kane-Potaka J;Tsusaka TW;Botha R;Rajendran A;Givens DI;Parasannanavar DJ;Subramaniam K;Prasad KDV;Vetriventhan M;Bhandari RK
通讯作者：
Bhandari RK
DOI：
10.22434/ifamr2017.0040
发表时间：
2018-01-01
影响因子：
1.5
作者：
Long, Thomas B.;Blok, Vincent
通讯作者：
Blok, Vincent
影响因子：
3.6
作者：
Alyami, Jaber;Whitehouse, Ella;Marciani, Luca
通讯作者：
Marciani, Luca
影响因子：
3.7
作者：
Chang CJ;Jian DY;Lin MW;Zhao JZ;Ho LT;Juan CC
通讯作者：
Juan CC
影响因子：
5.2
作者：
Balduzzi, Sara;Ruecker, Gerta;Schwarzer, Guido
通讯作者：
Schwarzer, Guido