A Suicide Prevention Intervention for Emerging Adult Sexual and Gender Minority Groups: Protocol for a Pilot Hybrid Effectiveness Randomized Controlled Trial.
A Suicide Prevention Intervention for Emerging Adult Sexual and Gender Minority Groups: Protocol for a Pilot Hybrid Effectiveness Randomized Controlled Trial.
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DOI：
10.2196/48177
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发表时间：
2023-09-29
影响因子：
1.7
通讯作者：
Bauermeister, Jose A.
中科院分区：
文献类型：
--
作者：
Brown, Lily A.;Webster, Jessica L.;Tran, Jennifer T.;Wolfe, James R.;Golinkoff, Jesse;Patel, Esha;Arcomano, Amanda C.;Ben Nathan, Jennifer;O'Connor, Alexander Azat;Zhu, Yiqin;Oquendo, Maria;Brown, Gregory K.;Mandell, David;Mowery, Danielle;Bauermeister, Jose A.
关键词：
自杀未遂和自杀死亡对性和性别少数新兴成年人（18-24岁）的影响不成比例。然而，针对新兴的成年性和性别少数群体（EA-SGM）的自杀预防策略并不普遍。安全计划干预（SPI）具有降低一般人群自杀风险的强有力证据，但目前尚不清楚如何最好地支持EA-SGM组使用安全计划。我们的干预措施（支持向成年过渡并减少自杀[STARS]）以现有的男男性行为青少年生活技能移动的应用程序（iREACH）的内容为基础，并寻求针对EA-SGM群体中自杀的核心风险因素，即积极影响、歧视和社会脱节。该移动的应用程序将提供给随机分配到STARS的参与者，同时提供6次同伴指导会议，以支持使用应用程序中的安全计划和其他生活技能，最终降低自杀风险。我们将试点测试同伴指导与基于应用程序的干预（STARS）的组合，旨在减少自杀意念和行为。STARS将包括自杀预防内容，并将针对积极影响，歧视和社会支持。在与临床医生进行面对面SPI之后，STARS用户可以访问内容和活动，以增加他们使用SPI的意图并克服其使用障碍。EA-SGM组将随机接受SPI单药治疗或STARS治疗，并进行6个月的评估。在RE-AIM（达到，有效性，采用，实施和维护）框架的指导下，我们将招募和入组60名报告上个月自杀意念的EA-SGM个体的种族和民族多样化样本。使用1型有效性-实施混合设计，受试者将被随机分配接受SPI（对照组）或接受SPI与STARS（干预组）。我们将跟踪参与者6个月，并在2、4和6个月时进行评估。初步有效性结果（自杀意念和行为）和假设的变化机制（积极影响，应对歧视和社会支持）将作为我们的主要结果。次要成果包括关键的实施指标，包括参与者的意愿和采用SPI和STARS以及工作人员在交付计划方面的经验。研究活动于2021年9月开始并正在进行中。该研究已获得宾夕法尼亚大学机构审查委员会的批准（方案编号849500）。研究招募于2022年10月14日开始。该项目将是第一个为有自杀风险的EA-SGM群体量身定制的移动干预措施之一。该项目针对这一人群的记录差距：处理选定家庭的方法，注重生命过程的观点，网络方法，并注重健康公平和提供与性和性别少数青年有关的额外服务。ClinicalTrials.gov NCT 05018143; https://classic.clinicaltrials.gov/ct2/show/NCT05018143 DERR 1 -10.2196/48177
Suicide attempts and suicide death disproportionately affect sexual and gender minority emerging adults (age 18-24 years). However, suicide prevention strategies tailored for emerging adult sexual and gender minority (EA-SGM) groups are not widely available. The Safety Planning Intervention (SPI) has strong evidence for reducing the risk for suicide in the general population, but it is unclear how best to support EA-SGM groups in their use of a safety plan. Our intervention (Supporting Transitions to Adulthood and Reducing Suicide [STARS]) builds on content from an existing life skills mobile app for adolescent men who have sex with men (iREACH) and seeks to target core risk factors for suicide among EA-SGM groups, namely, positive affect, discrimination, and social disconnection. The mobile app is delivered to participants randomized to STARS alongside 6 peer mentoring sessions to support the use of the safety plan and other life skills from the app to ultimately reduce suicide risk. We will pilot-test the combination of peer mentoring alongside an app-based intervention (STARS) designed to reduce suicidal ideation and behaviors. STARS will include suicide prevention content and will target positive affect, discrimination, and social support. After an in-person SPI with a clinician, STARS users can access content and activities to increase their intention to use SPI and overcome obstacles to its use. EA-SGM groups will be randomized to receive either SPI alone or STARS and will be assessed for 6 months. Guided by the RE-AIM (reach, efficacy, adoption, implementation, and maintenance) framework, we will recruit and enroll a racially and ethnically diverse sample of 60 EA-SGM individuals reporting past-month suicidal ideation. Using a type-1 effectiveness-implementation hybrid design, participants will be randomized to receive SPI (control arm) or to receive SPI alongside STARS (intervention arm). We will follow the participants for 6 months, with evaluations at 2, 4, and 6 months. Preliminary effectiveness outcomes (suicidal ideation and behavior) and hypothesized mechanisms of change (positive affect, coping with discrimination, and social support) will serve as our primary outcomes. Secondary outcomes include key implementation indicators, including participants’ willingness and adoption of SPI and STARS and staff’s experiences with delivering the program. Study activities began in September 2021 and are ongoing. The study was approved by the institutional review board of the University of Pennsylvania (protocol number 849500). Study recruitment began on October 14, 2022. This project will be among the first tailored, mobile-based interventions for EA-SGM groups at risk for suicide. This project is responsive to the documented gaps for this population: approaches that address chosen family, focus on a life-course perspective, web approaches, and focus on health equity and provision of additional services relevant to sexual and gender minority youth. ClinicalTrials.gov NCT05018143; https://classic.clinicaltrials.gov/ct2/show/NCT05018143 DERR1-10.2196/48177
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DOI：
10.1097/nmd.0000000000000533
发表时间：
2017-03
期刊：
The Journal of nervous and mental disease
影响因子：
--
作者：
Gaudiano BA;Wenze SJ;Weinstock LM;Tezanos KM;Miller IW
通讯作者：
Miller IW
影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
DOI：
10.1016/0749-5978(91)90020-t
发表时间：
1991-12-01
影响因子：
4.6
作者：
AJZEN, I
通讯作者：
AJZEN, I
影响因子：
9.9
作者：
Flesch, Rudolf
通讯作者：
Flesch, Rudolf
影响因子：
3.8
作者：
Bauermeister, Jose A.
通讯作者：
Bauermeister, Jose A.