Immunohistological studies of lymphoproliferative lesions in a fatal case of Epstein-Barr virus infection.
Immunohistological studies of lymphoproliferative lesions in a fatal case of Epstein-Barr virus infection.
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爱泼斯坦-巴尔病毒感染致死病例中淋巴增殖性病变的免疫组织学研究。
DOI：
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发表时间：
1986
影响因子：
3.4
通讯作者：
T. Azim
中科院分区：
文献类型：
--
作者：
P. Morgan‐Capner;J. Morris;M. McIllmurray;J. Thomas;D. Crawford;T. Azim
一例传染性单核细胞增多症的致死性病例发生在一个年轻的成年人。在他的母亲身上发现了异常的血清学特征，尽管没有其他家族史表明对EB病毒（EBV）的免疫反应存在遗传缺陷。使用一系列特异性单克隆和多克隆抗体分析尸检时获得的组织中观察到的细胞浸润。多克隆性浆细胞样B细胞增殖在许多组织中发生。这些细胞的EBV核抗原呈阳性，但在超微结构检查中未观察到病毒颗粒，且未分离出病毒，提示非允许性感染。
A fatal case of infectious mononucleosis occurred in a young adult. Abnormal serological features were noted in his mother, although there was no other family history suggesting an inherited defect of immune response to Epstein-Barr virus (EBV). The cellular infiltrate observed in tissues obtained at necropsy was analysed with a range of specific monoclonal and polyclonal antibodies. Polyclonal plasmacytoid B cell proliferation had occurred in many tissues. These cells were positive for EBV nuclear antigen, but viral particles were not seen on ultrastructural examination, and the virus was not isolated, suggesting a non-permissive infection.
一名 12 岁严重联合免疫缺陷患者骨髓移植后，不同克隆来源的 Epstein-Barr 病毒相关 B 细胞增殖。
DOI：
10.1056/nejm198505023121804
发表时间：
1985
期刊：
The New England journal of medicine
影响因子：
--
作者：
Shearer,WT;Ritz,J;Finegold,MJ;Guerra,IC;Rosenblatt,HM;Lewis,DE;Pollack,MS;Taber,LH;Sumaya,CV;Grumet,FC
通讯作者：
Grumet,FC
Epstein-Barr病毒诱导淋巴细胞增殖。
DOI：
10.1056/nejm198411013111806
发表时间：
1984
期刊：
The New England journal of medicine
影响因子：
--
作者：
Sullivan,JL;Medveczky,P;Forman,SJ;Baker,SM;Monroe,JE;Mulder,C
通讯作者：
Mulder,C