Conservation of BF-1 expression in amphioxus and zebrafish suggests evolutionary ancestry of anterior cell types that contribute to the vertebrate telencephalon

Conservation of BF-1 expression in amphioxus and zebrafish suggests evolutionary ancestry of anterior cell types that contribute to the vertebrate telencephalon
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文昌鱼和斑马鱼中 BF-1 表达的保守性表明,有助于脊椎动物端脑的前部细胞类型的进化祖先

DOI:
10.1007/s004270050200
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发表时间:
1998
影响因子:
2.4
通讯作者:
S. Krauss
S. Krauss
中科院分区:
生物学4区
文献类型:
--
作者:
H. Toresson;J. Martínez;Anne Bardsley;X. Caubit;S. Krauss

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Abstract The forkhead domain containing transcription factor BF-1 has been shown to play a major role in the correct development of the cerebral hemispheres in the mouse. BF-1 orthologs have been isolated from zebrafish and the cephalocordate amphioxus. In both species, BF-1 is expressed in the anterior neural tube. In zebrafish zBF-1 expression is restricted to anterior portions of the otic vesicle and to the presumptive telencephalon. In amphioxus AmphiBF-1 is transiently seen in the frontal part of the first somite and, at 3 days of development, in a small number of cells in the cerebral vesicle (cv). The anterior expression of BF-1 in chordates and vertebrates and of slp-1/2 in Drosophila suggests that BF-1 is crucial for an evolutionarily conserved specification of anterior neuronal cell types.
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