Venous oxygenation mapping using velocity-selective excitation and arterial nulling.

Venous oxygenation mapping using velocity-selective excitation and arterial nulling.
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DOI:
10.1002/mrm.24145
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发表时间:
2012-11
影响因子:
3.3
通讯作者:
Wong, Eric C.
Wong, Eric C.
中科院分区:
医学3区
文献类型:
--
作者:
Guo, Jia;Wong, Eric C.

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A new MRI technique to map the oxygenation of venous blood is presented. The method uses velocity-selective excitation and arterial nulling pulses, combined with phase sensitive signal detection to isolate the venous blood signal. The T2 of this signal along with a T2-Y calibration curve yields estimates of venous oxygenation in situ. Results from phantoms and healthy human subjects under normoxic and hypoxic conditions are shown, and venous saturation levels estimated from both sagittal sinus and grey matter based ROIs are compared to the related techniques TRUST and QUIXOTIC. In addition, combined with an additional scan without arterial nulling pulses, the oxygen saturation level on arterial side can also be estimated.
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