A randomized clinical trial of Cogmed Working Memory Training in school-age children with ADHD: a replication in a diverse sample using a control condition.
A randomized clinical trial of Cogmed Working Memory Training in school-age children with ADHD: a replication in a diverse sample using a control condition.
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DOI：
10.1111/jcpp.12146
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发表时间：
2014-03
期刊：
影响因子：
--
通讯作者：
Ramon M
中科院分区：
文献类型：
--
作者：
Chacko A;Bedard AC;Marks DJ;Feirsen N;Uderman JZ;Chimiklis A;Rajwan E;Cornwell M;Anderson L;Zwilling A;Ramon M
认知工作记忆训练（CWMT）作为治疗儿童注意力缺陷/多动障碍（ADHD）的一种有前景的干预措施而受到了广泛关注。与此同时，先前临床试验中的方法学缺陷使人们对 CWMT 的疗效提出质疑。特别是，CWMT 和之前试验中使用的 CWMT 安慰剂版本之间在 CWMT 的关键方面（即偶然强化、计算机训练完成任务时间、亲子互动、支持性辅导）缺乏等效性，这可能是 CWMT 获得有利结果的原因。 85 名 7 至 11 岁患有 ADHD 的学龄儿童（66 名男性；78%）被随机分配至标准 CWMT（CWMT Active）或控制良好的 CWMT 安慰剂组（CWMT Placebo），并在治疗前和治疗后 3 周进行评估。依赖性测量包括家长和老师对多动症症状的评分；注意力、活动水平和冲动的客观衡量；工作记忆和学业成绩的心理测量指数（临床试验标题：联合认知矫正和行为干预治疗注意力缺陷/多动障碍；http://clinicaltrials.gov/ct2/show/NCT01137318）。 CWMT Active 参与者在言语和非言语工作记忆存储方面表现出显着的改善，但在工作记忆存储和处理/操作方面没有明显的进步。此外，在任何其他结果指标上均未观察到治疗组差异。当使用更严格的比较条件时，CWMT 显示了对 ADHD 儿童工作记忆某些方面的影响；然而，CWMT 似乎并没有促进治疗推广到其他功能领域。因此，CWMT 不应被视为治疗多动症儿童的可行疗法。
Cogmed Working Memory Training (CWMT) has received considerable attention as a promising intervention for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in children. At the same time, methodological weaknesses in previous clinical trials call into question reported efficacy of CWMT. In particular, lack of equivalence in key aspects of CWMT (i.e., contingent reinforcement, time-on-task with computer training, parent-child interactions, supportive coaching) between CWMT and placebo versions of CWMT used in previous trials may account for the beneficial outcomes favoring CWMT. Eighty-five 7- to 11-year old school-age children with ADHD (66 male; 78%) were randomized to either standard CWMT (CWMT Active) or a well-controlled CWMT placebo condition (CWMT Placebo) and evaluated before and 3 weeks after treatment. Dependent measures included parent and teacher ratings of ADHD symptoms; objective measures of attention, activity level, and impulsivity; and psychometric indices of working memory and academic achievement (Clinical trial title: Combined cognitive remediation and behavioral intervention for the treatment of Attention-Deficit/Hyperactivity Disorder; http://clinicaltrials.gov/ct2/show/NCT01137318). CWMT Active participants demonstrated significantly greater improvements in verbal and nonverbal working memory storage, but evidenced no discernible gains in working memory storage plus processing/manipulation. In addition, no treatment group differences were observed for any other outcome measures. When a more rigorous comparison condition is utilized, CWMT demonstrates effects on certain aspects of working memory in children with ADHD; however, CWMT does not appear to foster treatment generalization to other domains of functioning. As such, CWMT should not be considered a viable treatment for children with ADHD.
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DOI：
10.1097/00004583-200104000-00008
发表时间：
2001-04-01
影响因子：
13.3
作者：
Sonuga-Barke, EJS;Daley, D;Weeks, A
通讯作者：
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DOI：
10.1097/00004583-200502000-00010
发表时间：
2005-02-01
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DOI：
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发表时间：
2013
期刊：
Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
影响因子：
--
作者：
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通讯作者：
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DOI：
10.1080/15374416.2010.517162
发表时间：
2010-01-01
影响因子：
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