An overview of naturally occurring histone deacetylase inhibitors.
An overview of naturally occurring histone deacetylase inhibitors.
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DOI：
10.2174/1568026615666141208105614
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发表时间：
2015
影响因子：
3.4
通讯作者：
Hong J
中科院分区：
文献类型：
--
作者：
Kim B;Hong J
Histone deacetylases (HDACs) have recently emerged as key elements in epigenetic control of gene expression. Due to the implication of HDACs in a variety of diseases ranging from cancer to neurodegenerative disorder, HDAC inhibitors have received increased attention in recent years. Over the last few decades, a myriad of HDAC inhibitors containing a wide variety of structural features have been identified from natural sources. Here, we review the discovery, synthesis, biological properties, and modes of action of these naturally occurring HDAC inhibitors and consider their implications for future research.
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影响因子：
5.2
作者：
Bowers AA;West N;Newkirk TL;Troutman-Youngman AE;Schreiber SL;Wiest O;Bradner JE;Williams RM
通讯作者：
Williams RM
影响因子：
64.8
作者：
Finnin, MS;Donigian, JR;Pavletich, NP
通讯作者：
Pavletich, NP
影响因子：
3.4
作者：
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通讯作者：
Nan, Fa-Jun
影响因子：
4.8
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Bottomley, Matthew J.;Lo Surdo, Paola;Carfi, Andrea
通讯作者：
Carfi, Andrea
影响因子：
15
作者：
Bowers, Albert;West, Nathan;Taunton, Jack;Schreiber, Stuart L.;Bradner, James E.;Williams, Robert M.
通讯作者：
Williams, Robert M.