Molecular motors for DNA translocation in prokaryotes.
Molecular motors for DNA translocation in prokaryotes.
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DOI:
10.1016/j.copbio.2011.12.023
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发表时间:
2012-08
影响因子:
7.7
通讯作者:
Smith, Douglas E.
中科院分区:
文献类型:
--
作者:
Allemand, Jean-Francois;Maier, Berenike;Smith, Douglas E.
DNA transport is an essential life process. From chromosome separation during cell division or sporulation, to DNA virus ejection or encapsidation, to horizontal gene transfer, it is ubiquitous in all living organisms. Directed DNA translocation is often energetically unfavorable and requires an active process that uses energy, namely the action of molecular motors. In this review we present recent advances in the understanding of three molecular motors involved in DNA transport in prokaryotes, paying special attention to recent studies using single-molecule techniques. We first discuss DNA transport during cell division, then packaging of DNA in phage capsids, and then DNA import during bacterial transformation.
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