HIV cure: an acceptability scientific agenda.
HIV cure: an acceptability scientific agenda.
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DOI：
10.1097/coh.0000000000000771
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发表时间：
2023-01-01
影响因子：
4.1
通讯作者：
Kyei, George B. B.
中科院分区：
文献类型：
--
作者：
Bonney, Evelyn Y. Y.;Lamptey, Helena;Kyei, George B. B.
近年来，对艾滋病毒治疗研究进行了重大投资，寻求永久治愈或缓解。这一审查的目的是考虑如何扩大这一重要的研究议程，以包括不同人群的可接受性和适当性问题。我们讨论了如何治愈的定义，如功能性治愈（缓解）或完全治愈（病毒消除）可以不同的人群解释。我们还讨论了不同的治疗方法，以及将非洲纳入治疗研究的重要性，以确保新出现的治疗方法可以在艾滋病流行病首当其冲的非洲大陆试用和利用。我们建议艾滋病治疗可接受性的社会科学研究应该与基础和临床科学同时进行，以确保治疗方法考虑利益相关者的偏好。
Recent years have seen major investments into HIV cure research, seeking a permanent cure or remission. The purpose of this review is to consider how this important research agenda could be broadened to include issues of acceptability and appropriateness for different populations. We discuss how the definitions of cure such as functional cure (remission) or complete cure (viral elimination) could be interpreted differently by various populations. We also discuss the different methods of cure and the importance of including Africa in cure research to ensure that emerging remedies could be trialled and utilized on the continent that bears the brunt of the AIDS pandemic. We propose that the social science research of HIV cure acceptability should be done concurrently with the basic and clinical sciences, to ensure that cure methods consider stakeholder preferences.
影响因子：
5.5
作者：
Rokx C;Prins HAB;Vandekerckhove L;Fidler SJ;Frater J;Bracchi M;Søgaard OS;Tolstrop M;Rasmussen TA;Salgado M;Blanco J;Martinez-Picado J;Clotet B;Tambussi G;Groenendijk A;Verbon A;Boucher CAB
通讯作者：
Boucher CAB
影响因子：
1.7
作者：
Moodley K;Staunton C;de Roubaix M;Cotton M
通讯作者：
Cotton M